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  4. Recombinant Drosophila melanogaster Autophagy protein 5 (Atg5)

Recombinant Drosophila melanogaster Autophagy protein 5 (Atg5)

  • 中文名称：
    Recombinant Drosophila melanogaster Autophagy protein 5(Atg5),Yeast
  • 货号：
    CSB-YP895235DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Autophagy protein 5(Atg5),Yeast
  • 货号：
    CSB-EP895235DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Autophagy protein 5(Atg5),Yeast
  • 货号：
    CSB-EP895235DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Autophagy protein 5(Atg5),Yeast
  • 货号：
    CSB-BP895235DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Autophagy protein 5(Atg5),Yeast
  • 货号：
    CSB-MP895235DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Atg5; CG1643Autophagy protein 5; APG5-like
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-269
  • 氨基酸序列
    MAHDREVLRM IWEGQIGICF QADRDEIVGI KPEPFYLMIS RLSYLPLVTD KVRKYFSRYI SAEHQDGAVW FDFNGTPLRL HYPIGVLYDL LHPEEDSTPW CLTIHFSKFP EDMLVKLNSK ELLESHYMSC LKEADVLKHR GLVISAMQKK DHNQLWLGLV NEKFDQFWAV NRRLMEPYGD LESFKNIPLR IYTDDDFTYT QKLISPISVG GQKKSLADLM AELSTPVRRA VGCRTHGIDL HEETQLQWMS EHLSYPDNFL HLSVDYKDV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in autophagic vesicle formation. Conjugation with Atg12, through a ubiquitin-like conjugating system involving Atg7 as an E1-like activating enzyme and Atg10 as an E2-like conjugating enzyme, is essential for its function. The Atg12-Atg5 conjugate acts as an E3-like enzyme which is required for lipidation of Atg8 and its association to the vesicle membranes.
  • 基因功能参考文献：
    1. Studies show that the TOR signaling pathway and ATG5 and ATG7 are crucial for the regulation of cellular processes and can play various functions in different cell types in the brain. PMID: 28196106
  • 亚细胞定位：
    Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
  • 蛋白家族：
    ATG5 family
  • 数据库链接：

    KEGG: dme:Dmel_CG1643

    STRING: 7227.FBpp0071023

    UniGene: Dm.33486