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  4. Recombinant Drosophila melanogaster High mobility group protein DSP1 (Dsp1)

Recombinant Drosophila melanogaster High mobility group protein DSP1 (Dsp1)

  • 中文名称：
    黑腹果蝇Dsp1重组蛋白
  • 货号：
    CSB-YP638766DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Dsp1重组蛋白
  • 货号：
    CSB-EP638766DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Dsp1重组蛋白
  • 货号：
    CSB-EP638766DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Dsp1重组蛋白
  • 货号：
    CSB-BP638766DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Dsp1重组蛋白
  • 货号：
    CSB-MP638766DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Dsp1
  • Uniprot No.：
  • 别名：
    Dsp1; ssrp2; CG12223; High mobility group protein DSP1; Protein dorsal switch 1
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-393
  • 氨基酸序列
    MEHFHQIQQT IQHYQQQLAA QQQQQVQQQQ LQQHQVVVQQ NQQQAHQNSS NTTAGVGTQQ LFTYKMASSF PNPATTMAQV VATSNAAGTT GYDYRLNMAQ AAAAAAVPGS QWWYSAANQG QVDANTAAQL QHQQQQQQQQ QQQQQQQHQQ QQQMQQQQQQ QNVINSASPM SRVKADAKPR GRMTAYAYFV QTCREEHKKK HPDETVIFAE FSRKCAERWK TMVDKEKKRF HEMAEKDKQR YEAEMQNYVP PKGAVVGRGK KRKQIKDPNA PKRSLSAFFW FCNDERNKVK ALNPEFGVGD IAKELGRKWS DVDPEVKQKY ESMAERDKAR YEREMTEYKT SGKIAMSAPS MQASMQAQAQ KAALLAAAAQ QQHQQLEEQH DDDDGDGDDD ENQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Binds preferentially single-stranded DNA and unwinds double-stranded DNA.
  • 基因功能参考文献：
    1. involved in the regulation of the kni gap gene PMID: 12820172
    2. binding of DSP1 to Polycomb response elements is important for the recruitment of Polycomb group proteins PMID: 15791260
    3. affects gene expression regulation in Drosophila. PMID: 16115448
    4. DSP1 and corto proteins co-localize at 91 sites on polytene chromosomes and co-immunoprecipitate in embryos. PMID: 16613610
    5. Molecular modeling was used to compare the tertiary structure of Dsp1 with two other Drosophila proteins. PMID: 17785540
    6. While Dorsal seems to be nuclearly localized in ventral nuclei, it is actively shuttling into and out of all nuclei, including nuclei on the dorsal side. PMID: 17978003

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  • 亚细胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    HMGB family
  • 数据库链接：

    KEGG: dme:Dmel_CG12223

    STRING: 7227.FBpp0288398

    UniGene: Dm.2879