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  4. Recombinant Drosophila melanogaster Histone H3 (His3)

Recombinant Drosophila melanogaster Histone H3 (His3)

  • 中文名称：
    黑腹果蝇His3;重组蛋白
  • 货号：
    CSB-YP365735DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇His3;重组蛋白
  • 货号：
    CSB-EP365735DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇His3;重组蛋白
  • 货号：
    CSB-EP365735DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇His3;重组蛋白
  • 货号：
    CSB-BP365735DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇His3;重组蛋白
  • 货号：
    CSB-MP365735DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    His3;
  • Uniprot No.：
  • 别名：
    His3;; His3:CG31613; CG31613;; His3:CG33803; CG33803;; His3:CG33806; CG33806;; His3:CG33809; CG33809;; His3:CG33812; CG33812;; His3:CG33815; CG33815;; His3:CG33818; CG33818;; His3:CG33821; CG33821;; His3:CG33824; CG33824;; His3:CG33827; CG33827;; His3:CG33830; CG33830;; His3:CG33833; CG33833;; His3:CG33836; CG33836;; His3:CG33839; CG33839;; His3:CG33842; CG33842;; His3:CG33845; CG33845;; His3:CG33848; CG33848;; His3:CG33851; CG33851;; His3:CG33854; CG33854;; His3:CG33857; CG33857;; His3:CG33860; CG33860;; His3:CG33863; CG33863;; His3:CG33866; CG33866; Histone H3
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-136
  • 氨基酸序列
    ARTKQTARK STGGKAPRKQ LATKAARKSA PATGGVKKPH RYRPGTVALR EIRRYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSSAV MALQEASEAY LVGLFEDTNL CAIHAKRVTI MPKDIQLARR IRGERA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
  • 基因功能参考文献：
    1. Acetylation of histone H3 lysine 23 is localized to promoters and correlates with endogenous ecdysone induced gene activation. PMID: 22808194
    2. In Su(var)3-9 null mutants, H3-K9 methylation at chromocentre heterochromatin is strongly reduced, indicating that SU(VAR)3-9 is the major heterochromatin-specific HMTase in Drosophila. PMID: 11867540
    3. Phosphorylation of H3 is linked to transcription and can be modulated by the structure of the promoter. PMID: 12514098
  • 亚细胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    Histone H3 family
  • 数据库链接：

    KEGG: dme:Dmel_CG31613

    STRING: 7227.FBpp0091112