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  4. Recombinant Drosophila melanogaster Lachesin (Lac)

Recombinant Drosophila melanogaster Lachesin (Lac)

  • 货号：
    CSB-YP636554DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP636554DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP636554DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP636554DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP636554DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Lac
  • Uniprot No.：
  • 别名：
    Lac; CG12369Lachesin
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    26-336
  • 氨基酸序列
    QRTPT ISYITQEQIK DIGGTVEFDC SVQYAKEYNV LFLKTDSDPV FLSTGSTLVI KDSRFSLRYD PNSSTYKLQI KDIQETDAGT YTCQVVISTV HKVSAEVKLS VRRPPVISDN STQSVVASEG SEVQMECYAS GYPTPTITWR RENNAILPTD SATYVGNTLR IKSVKKEDRG TYYCVADNGV SKGDRRNINV EVEFAPVITV PRPRLGQALQ YDMDLECHIE AYPPPAIVWT KDDIQLANNQ HYSISHFATA DEYTDSTLRV ITVEKRQYGD YVCKATNRFG EAEARVNLFE TIIPVCPPAC GQAYIA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for normal tracheal development and maintenance of the trans-epithelial diffusion barrier. Functions as a homophilic cell-adhesion molecule. May play a role in early neuronal differentiation and axon outgrowth.
  • 基因功能参考文献：
    1. Lac co-localizes with Septate Junction proteins and accumulates specifically at this type of cellular junction. PMID: 14681183
    2. Here, we report that Drosophila Lachesin (Lac), a septate junction component, is required for a functional blood brain barrier. PMID: 16682215
  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Note=Located at the extracellular face of the membrane and becomes associated with septate junctions.
  • 组织特异性：
    Expressed on differentiating neuronal cells from the onset of neurogenesis in both the central and peripheral nervous systems. First detected in the cellularized blastoderm, apart from in the ventral side. Expression persists uniformly in the early ectode
  • 数据库链接：

    KEGG: dme:Dmel_CG12369

    STRING: 7227.FBpp0087044

    UniGene: Dm.4470