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  4. Recombinant Drosophila melanogaster Methyltransferase-like protein 14 homolog (CG7818)

Recombinant Drosophila melanogaster Methyltransferase-like protein 14 homolog (CG7818)

  • 中文名称：
    Recombinant Drosophila melanogaster Methyltransferase-like protein 14 homolog(CG7818),Yeast
  • 货号：
    CSB-YP896115DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Methyltransferase-like protein 14 homolog(CG7818),Yeast
  • 货号：
    CSB-EP896115DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Methyltransferase-like protein 14 homolog(CG7818),Yeast
  • 货号：
    CSB-EP896115DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Methyltransferase-like protein 14 homolog(CG7818),Yeast
  • 货号：
    CSB-BP896115DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Methyltransferase-like protein 14 homolog(CG7818),Yeast
  • 货号：
    CSB-MP896115DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CG7818
  • Uniprot No.：
  • 别名：
    Mettl14; KAR4; CG7818; N6-adenosine-methyltransferase non-catalytic subunit; Karyogamy protein 4; Methyltransferase-like protein 14; dMettl14
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-397
  • 氨基酸序列
    MSDVLKSSQE RSRKRRLLLA QTLGLSSVDD LKKALGNAED INSSRQLNSG GQREEEDGGA SSSKKTPNEI IYRDSSTFLK GTQSSNPHND YCQHFVDTGQ RPQNFIRDVG LADRFEEYPK LRELIKLKDK LIQDTASAPM YLKADLKSLD VKTLGAKFDV ILIEPPLEEY ARAAPSVATV GGAPRVFWNW DDILNLDVGE IAAHRSFVFL WCGSSEGLDM GRNCLKKWGF RRCEDICWIR TNINKPGHSK QLEPKAVFQR TKEHCLMGIK GTVRRSTDGD FIHANVDIDL IISEEEEFGS FEKPIEIFHI IEHFCLGRRR LHLFGRDSSI RPGWLTVGPE LTNSNFNSEL YQTYFAEAPA TGCTSRIELL RPKSPPPNSK VLRGRGRGFP RGRGRPR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Non-catalytic component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. In the heterodimer formed with Ime4/Mettl3, Mettl14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions.
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    MT-A70-like family
  • 数据库链接：

    KEGG: dme:Dmel_CG7818

    STRING: 7227.FBpp0079219

    UniGene: Dm.351