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  4. Recombinant Drosophila melanogaster Probable insulin-like peptide 6 (Ilp6)

Recombinant Drosophila melanogaster Probable insulin-like peptide 6 (Ilp6)

  • 中文名称：
    黑腹果蝇Ilp6重组蛋白
  • 货号：
    CSB-YP893843DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Ilp6重组蛋白
  • 货号：
    CSB-EP893843DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Ilp6重组蛋白
  • 货号：
    CSB-EP893843DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Ilp6重组蛋白
  • 货号：
    CSB-BP893843DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Ilp6重组蛋白
  • 货号：
    CSB-MP893843DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ilp6
  • Uniprot No.：
  • 别名：
    Ilp6; CG14049; Probable insulin-like peptide 6; dILP6; Insulin-related peptide 6) [Cleaved into: Probable insulin-like peptide 6 A chain; Probable insulin-like peptide 6 B chain]
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    34-107
  • 氨基酸序列
    SPLAPTE YEQRRMMCST GLSDVIQKIC VSGTVALGDV FPNSFGKRRK RDLQNVTDLC CKSGGCTYRE LLQYCKG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. it was demonstrated for the first time that insulin-like DILP6 protein in drosophila influences the level of octopamine (regulating the activity of the enzyme degrading octopamine). PMID: 29368833
    2. suggest a feedback system in the interaction between juvenile hormone and DILP6 in which DILP6 negatively regulates the JH titre via an increase in the hormone degradation and a decrease in its synthesis PMID: 27823956
    3. Fat body-derived Drosophila insulin-like peptide 6 induces lipid uptake in oenocytes, promoting lipid turnover during fasting and increasing starvation tolerance. PMID: 25472843
    4. Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain. PMID: 22935001
    5. Study shows that during metamorphosis, when feeding stops, a specific DILP (Dilp6) is produced by the fat body and relays the growth signal; expression of DILP6 during pupal development is controlled by the steroid hormone ecdysone. PMID: 20059956
    6. Shows that Drosophila insulin-like peptide 6 (DILP6), which is structurally similar to vertebrate insulin-like growth factor (IGF), is predominantly expressed in the fat body, a functional equivalent of the vertebrate liver and adipocytes. PMID: 20059957

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Insulin family
  • 组织特异性：
    Expressed at a low level in the larval gut.
  • 数据库链接：

    KEGG: dme:Dmel_CG14049

    STRING: 7227.FBpp0070390

    UniGene: Dm.31063