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  4. Recombinant Drosophila melanogaster Protein matrimony (mtrm)

Recombinant Drosophila melanogaster Protein matrimony (mtrm)

  • 中文名称：
    黑腹果蝇mtrm重组蛋白
  • 货号：
    CSB-YP637578DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇mtrm重组蛋白
  • 货号：
    CSB-EP637578DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇mtrm重组蛋白
  • 货号：
    CSB-EP637578DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇mtrm重组蛋白
  • 货号：
    CSB-BP637578DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇mtrm重组蛋白
  • 货号：
    CSB-MP637578DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    mtrm
  • Uniprot No.：
  • 别名：
    mtrm; anon-D52; CG18543; Protein matrimony; Cell cycle arrest protein D52
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-217
  • 氨基酸序列
    MENSRTPTNK TKITLNRTPT LKERRWNTLK VNTSNVRCST PIFGNFRSPN LSPIENMGTK GKSPVSPMRF ATFKKVPTKV HPKQQQQQQH QHCHRTQLKP PPFVLPKPQE EIIEPEREIK SCSSPDTCSD DSNMETSLAL ESRRRSIKAS NHSYVVNHAA NVEQILMHMG LENYVTNFEE AHIDLVELAS LERADLVKIG LNTDEDCNRI MDVLHTL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Polo kinase inhibitor required to maintain G2 arrest in the meiotic cell cycle in females. Holds heterochromatically paired homologs together from the end of pachytene until metaphase I. Haploinsufficient locus for homologous achiasmate segregation and may be required for the maintenance of heterochromatic pairings.
  • 基因功能参考文献：
    1. We showed that Mtrm is subject to APC(Cort)-mediated proteasomal degradation and have identified a putative APC/C recognition motif in Mtrm that when mutated partially stabilized the protein in the embryo. PMID: 24019759
    2. Binding of Drosophila Polo kinase to its regulator Matrimony is noncanonical and involves two separate functional domains. PMID: 23479640
    3. In female meiosis, Mtrm regulates Polo's role in promoting nuclear envelope breakdown and the subsequent entry of the oocyte into prometaphase. PMID: 18245949
  • 亚细胞定位：
    Nucleus. Chromosome.
  • 数据库链接：

    KEGG: dme:Dmel_CG18543

    STRING: 7227.FBpp0076340

    UniGene: Dm.891