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  4. Recombinant Drosophila melanogaster Protein painting of fourth (Pof)

Recombinant Drosophila melanogaster Protein painting of fourth (Pof)

  • 中文名称：
    黑腹果蝇Pof重组蛋白
  • 货号：
    CSB-YP893358DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Pof重组蛋白
  • 货号：
    CSB-EP893358DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Pof重组蛋白
  • 货号：
    CSB-EP893358DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Pof重组蛋白
  • 货号：
    CSB-BP893358DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Pof重组蛋白
  • 货号：
    CSB-MP893358DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Pof
  • Uniprot No.：
  • 别名：
    Pof; CG3691; Protein painting of fourth; Zeste-interacting protein 16; Zip16
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-495
  • 氨基酸序列
    MDSKRAALES GDGPDAKRLD TTDDQDKEAS GGDGSQVMLA KHVAPYTGHG CTPPMESYLF EPTPAGSQLL PWKTSVDLDN DAELEKPTSD KKPDTAKLSR RELAKMRREH TLRALALERE LTNKPGQTPA SEVLLVRFPD PEITAPMLAG LSKDIRDVVL PISVAPRYCL VHLKAGADVE ATICDINRVR FGTGHLRAEL KPFSDEEQAE FIDPCSLYVG NIPFNMTTSA IKAYFANAMR VDIGVLKREK RARYAFVRYA SPDQTMEAFK ELVDSPLNSR TLTVRYRRLR KRAGMPMVQC ATSFQALQSP NGDDDNTDCK VISPPPLESI IISDSDNCSD SSGNGKEDGK RKKKINEQER EIEKLKRQMA EYGAIIKSLQ FRQNSLEDTF IPDLTPKVEP SVNPTGCLLG SNAVHLMRDI KKECDYLGIP DPVPATKPTT QAQDDSQKKA KRSCFGRLFT GPFRRGTSAM KTADEYEKDD RLEELYAQLE RDPDP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable RNA-binding protein that specifically binds to the fourth chromosome and may bind an RNA that spreads the fourth chromosome. May be a reminiscence of X chromosome dosage compensation of ancestral Drosophila species in which the X and the fourth chromosomes are one single chromosome.
  • 基因功能参考文献：
    1. The targeting of protein Painting of fourth to PoX1(POF-on-X) and PoX2 is largely dependent on roX expression and identified a high-affinity target region that ectopically recruits POF. PMID: 23733888
    2. POF binds to nascent RNA, and this binding is associated with increased transcription output from chromosome 4 PMID: 22473994
    3. POF is involved in a chromosome-specific regulatory function PMID: 15210994
  • 亚细胞定位：
    Nucleus. Chromosome. Note=Specifically binds to the fourth chromosome.
  • 组织特异性：
    Weakly expressed in embryos. Expression increases during larval and pupal stages. In adults, it is predominantly expressed in males, while it is weakly expressed in females.
  • 数据库链接：

    KEGG: dme:Dmel_CG3691

    STRING: 7227.FBpp0072234

    UniGene: Dm.2706