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  4. Recombinant Drosophila melanogaster Protein twisted gastrulation (tsg)

Recombinant Drosophila melanogaster Protein twisted gastrulation (tsg)

  • 货号：
    CSB-YP344956DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP344956DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP344956DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP344956DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP344956DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    tsg
  • Uniprot No.：
  • 别名：
    tsg; CG1502; Protein twisted gastrulation
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    24-249
  • 氨基酸序列
    DGCNEVV CGSVVSKCLI TQSCQCKLND CHCCKDCLNC LGELYIECCG CLDMCPKHKD VLPSLTPRSE IGDIEGVPEL FDTLTAEDDE GWSTIRFSMR AGFKQRVQGG ASGDAGNGNG NGNAGSAGVT LCTVIYVNSC IRANKCRQQC ESMGASSYRW FHDGCCECVG ENCLNYGINE SRCRGCPEDQ DQLLTADTVP AEAEQDLERF FGNEEIEDEW GYGEEDEFS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in dorsal-ventral patterning. Required for specification of a narrow strip of dorsal midline cells that will give rise to the amnioserosa, but not for specification of dorsal ectoderm cells. Inhibits BMP signaling; enhances the binding of sog to dpp, thus enhancing the antagonistic activity of sog.
  • 基因功能参考文献：
    1. Robustness of the BMP morphogen gradient in Drosophila embryonic patterning PMID: 12239569
    2. Data suggest that decapentaplegic (Dpp)concentration dependence, together with movement of Dpp by Sog and Tsg proteins, can explain how Tld activity is confined to the dorsal-most region of the embryo. PMID: 12925593
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Twisted gastrulation protein family
  • 组织特异性：
    First appears in stage 4 embryos, expressed in two domains: a broad mid-dorsal saddle and an anterior cap, expression between the domains is continuous across the dorsal midline. At stage 5, expression is refined into 4 graded stripes in the mid-dorsal re
  • 数据库链接：

    KEGG: dme:Dmel_CG1502

    STRING: 7227.FBpp0073426

    UniGene: Dm.27553