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  4. Recombinant Drosophila melanogaster Putative proteasome inhibitor (CG8979)

Recombinant Drosophila melanogaster Putative proteasome inhibitor (CG8979)

  • 中文名称：
    黑腹果蝇PI31重组蛋白
  • 货号：
    CSB-YP892687DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇PI31重组蛋白
  • 货号：
    CSB-EP892687DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇PI31重组蛋白
  • 货号：
    CSB-EP892687DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇PI31重组蛋白
  • 货号：
    CSB-BP892687DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇PI31重组蛋白
  • 货号：
    CSB-MP892687DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PI31
  • Uniprot No.：
  • 别名：
    PI31; CG8979; Proteasome inhibitor PI31 subunit
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-270
  • 氨基酸序列
    MESGSTAKTG DFFYGWDLLY KTVKADVSKK SDLLIALVHF LLTKHYNFRC VGVGDDKTLP EEEGSELLPD SWNDDDTKYS LRYVHDKMLY LLLGHITEGS LLINLLDINT KKVSNICVEP ETLVPEVKGG ITTIMPSASE IVERYRRELL DPVFTGNSRE VTTQTTNSPR PIGSDPDPLR IGEPRRGGSF IPSAFEPRPF GFPDVGRGDL DPLGRGGHGN LFSFPSRPNM GPGPVPRFDP FNPLNPNRPG QGGINPDHMR PPDWNPDYYM
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays an important role in the control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Enhances 26S proteasome function by promoting its assembly through the interaction with the assembly chaperones PSMD9 and PMSD5. Functions together with ntc to control non-apoptotic caspase activation during sperm individualization. In testis, is required for proper protein degradation and germline cell cycle progression.
  • 基因功能参考文献：
    1. Study identified DmPI31 as a binding partner of the F box protein Nutcracker, a component of an SCF ubiquitin ligase (E3) required for caspase activation during sperm differentiation in Drosophila. PMID: 21529711
  • 亚细胞定位：
    Cytoplasm. Note=In the spermatid, localizes to the actin-based individualization complex.
  • 蛋白家族：
    Proteasome inhibitor PI31 family
  • 组织特异性：
    In testis, expressed in germline stem cells and primary spermatocytes (at protein level).
  • 数据库链接：

    KEGG: dme:Dmel_CG8979

    STRING: 7227.FBpp0301842

    UniGene: Dm.4218