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  4. Recombinant Drosophila melanogaster Transcription factor Dp (Dp)

Recombinant Drosophila melanogaster Transcription factor Dp (Dp)

  • 中文名称：
    黑腹果蝇Dp重组蛋白
  • 货号：
    CSB-YP637589DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Dp重组蛋白
  • 货号：
    CSB-EP637589DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Dp重组蛋白
  • 货号：
    CSB-EP637589DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Dp重组蛋白
  • 货号：
    CSB-BP637589DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Dp重组蛋白
  • 货号：
    CSB-MP637589DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Dp
  • Uniprot No.：
  • 别名：
    Dp; CG4654; Transcription factor Dp
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-445
  • 氨基酸序列
    MAHSTGGTVK TDEVNFFFRN EHGQISKMLK PAQNKSEMEG GKPVAVVYAT GSSARNSGSA SGIGNVGRMG AFSQMGSQGQ FIRLQDNGLS IPKTEAGTTY TTVSAQKTSG AGSGHYDLPL KGDRYVKFTP NPIKMKSKLH AIQSNSLHSM SASSSSVQRK RKPDKAGKGL RHFSMKVCEK VEEKGKTTYN EVADDLVSEE MKNNAYDNNC DQKNIRRRVY DALNVLMAIN VISKDKKEIR WIGLPANSTE TFLALEEENC QRRERIKQKN EMLREMIMQH VAFKGLVERN KRNESQGVVP SPNASIQLPF IIVNTHKSTK INCSVTNDKS EYIFKFDKTF EMHDDIEVLK RMGFLLGLDK GECTPENIER VKSWVPPNLA KYVEAYGTGK TGENMYESDD EDNEFNGYLE SANESQGFAQ HSAQHTTDGE FKLEMDDDEL DDDID
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In follicle cells, the complex plays a central role in the site-specific DNA replication at the chorion loci. During development, the complex represses transcription of developmentally controlled E2F target genes. Can stimulate E2F-dependent transcription.
  • 基因功能参考文献：
    1. These findings identify a key function of E2F/Dp in skeletal muscle required for animal viability, and illustrate how the cell cycle regulator is repurposed in post-mitotic cells. PMID: 26823289
    2. Dampened transcriptional activation by E2F1-DP and Myb-MuvB is important to repress mitosis and coordinate the endocycle transcription PMID: 21045111
    3. dDP is required for normal cell proliferation, for optimal DNA synthesis, and for efficient G2/M progression. PMID: 15798191
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    E2F/DP family
  • 数据库链接：

    KEGG: dme:Dmel_CG4654

    STRING: 7227.FBpp0086853

    UniGene: Dm.6412