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  4. Recombinant Fruit fly Accessory gland-specific peptide 70A (SP)

Recombinant Fruit fly Accessory gland-specific peptide 70A (SP)

  • 中文名称：
    黑腹果蝇SP重组蛋白
  • 货号：
    CSB-YP356570DLU
  • 规格：
    ￥2832
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    SP
  • Uniprot No.：
  • 别名：
    SP; Acp70A; PAPB; CG17673Accessory gland-specific peptide 70A; Paragonial peptide B; Sex peptide; SP
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Full Length of Mature Protein
  • 来源：
    Yeast
  • 分子量：
    4.3kDa
  • 表达区域：
    20-55aa
  • 氨基酸序列
    WEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGRC
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    Tag-Free
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila. Binds initially to sperm where it is later cleaved to release an active peptide within the female reproductive tract. Signals via the sex peptide receptor (SPR) in female flies; may also act via other receptors. Moderates the activity of distinct neuronal circuitries in the female genital tract to promote specific PMRs including: enhanced ovulation, increased egg laying rate, increased feeding/foraging rate, induced antimicrobial peptide synthesis, reduced mating receptivity, reduced day-time sleep and reduced lifespan in multiple mated females.
  • 基因功能参考文献：
    1. Molecular Functions and Cross-Species Activity of Sex-Peptide in Drosophila PMID: 26022240
    2. sex peptide is required for normal magnitude and persistence of postmating responses PMID: 12893873
    3. sex peptide is the major agent eliciting the short-term and the long-term postmating responses PMID: 12897240
    4. Drosophila sex-peptide stimulates female innate immune system after mating via the Toll and Imd pathways. PMID: 16169493
    5. Copulation strongly stimulates female food intake and Sex Peptide is the main agent controlling this behavioral paradigm. PMID: 16581515
    6. SP acts by chemical mimicry of sugar components of the bacterial cell wall. Thus, SP may induce the immune system via pattern recognition receptors. PMID: 17922838
    7. Data show significant variation in expression levels of the SP gene Acp70A across D. melanogaster isolines. PMID: 19640319

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Drosophila sex peptide family
  • 组织特异性：
    Main cells of the accessory glands of males (paragonial gland).
  • 数据库链接：

    KEGG: dme:Dmel_CG17673

    STRING: 7227.FBpp0075572

    UniGene: Dm.2898