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  4. Recombinant Guanine nucleotide-binding protein alpha-16 subunit (gpa-16)

Recombinant Guanine nucleotide-binding protein alpha-16 subunit (gpa-16)

  • 中文名称：
    秀丽隐杆线虫gpa-16重组蛋白
  • 货号：
    CSB-YP863090CXY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    秀丽隐杆线虫gpa-16重组蛋白
  • 货号：
    CSB-EP863090CXY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    秀丽隐杆线虫gpa-16重组蛋白
  • 货号：
    CSB-EP863090CXY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    秀丽隐杆线虫gpa-16重组蛋白
  • 货号：
    CSB-BP863090CXY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    秀丽隐杆线虫gpa-16重组蛋白
  • 货号：
    CSB-MP863090CXY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    gpa-16
  • Uniprot No.：
  • 别名：
    gpa-16; spn-1; Y95B8A.5Guanine nucleotide-binding protein alpha-16 subunit
  • 种属：
    Caenorhabditis elegans
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-357
  • 氨基酸序列
    GCIMSQEDE AAKRRSKKID RLLKEDGENS MRTIKLLLLG AGESGKSTIL KQMRIIHDVG YTTEERKVFR GVVYGNIILS LNAIIHAMEQ LKISFTTLDH ESDARKLLMF STTGEEDELP EELVVLMKSV WSDSGIQKAL ERSREYQLND SAGYYLSQLD RICAPNYIPT QDDILRTRIK TTGIVETQFV YKDRLFLVFD VGGQRSERKK WIHCFEDVTA LIFCVALSEY DMVLVEDCQT NRMRESLKLF DSICNNKWFV ETSIILFLNK KDLFEEKIVR SPLTHCFPEY TGANNYEEAS AYIQQQFEDM NKRTTGEKNQ EIYTQFTCAT DTNNIRFVFD AVTDIIIRDN LRTCGLY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. In the 1-cell embryo, probably together with goa-1, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisons, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle.
  • 基因功能参考文献：
    1. findings show that the GoLoco-containing proteins GPR-1 and GPR-2, as well as the Galpha subunits GOA-1 and GPA-16, were essential for generation of proper pulling forces in asymmetric spindle positioning PMID: 12750478
    2. Data show that the asymmetry of GPR-1/2 (which act with GOA-1 and GPA-16) localization depends on PAR-3 and its downstream intermediate LET-99, as well as on the MES-1/SRC-1 signaling pathway. PMID: 14534135
    3. Results show that the spn-1 gene encodes the Galpha protein GPA-16, which appears to be required for centrosomal association of a Gbeta protein. PMID: 14534142
    4. requirement toward GPA-16 is distinct from the known function of RIC-8 in enabling interaction between Galpha proteins and GPR-1/2 PMID: 16162648
  • 蛋白家族：
    G-alpha family
  • 数据库链接：

    KEGG: cel:CELE_Y95B8A.5

    STRING: 6239.Y95B8A.5.1

    UniGene: Cel.16247