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  4. Recombinant Human BPI fold-containing family B member 4 (BPIFB4)

Recombinant Human BPI fold-containing family B member 4 (BPIFB4)

  • 货号：
    CSB-YP003694HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP003694HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP003694HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP003694HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP003694HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    BPIFB4
  • Uniprot No.：
  • 别名：
    BPI fold-containing family B member 4; Bpifb4; C20orf186; dJ726C3.5; Gm1006; Ligand-binding protein RY2G5; Long palate; lung and nasal epithelium carcinoma-associated protein 4; LPLC4_HUMAN; Lplunc4
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    19-614
  • 氨基酸序列
    SH ETNTVLRVTK DVLSNAISGM LQQSDALHSA LREVPLGVGD IPYNDFHVRG PPPVYTNGKK LDGIYQYGHI ETNDNTAQLG GKYRYGEILE SEGSIRDLRN SGYRSAENAY GGHRGLGRYR AAPVGRLHRR ELQPGEIPPG VATGAVGPGG LLGTGGMLAA DGILAGQGGL LGGGGLLGDG GLLGGGGVLG VLGEGGILST VQGITGLRIV ELTLPRVSVR LLPGVGVYLS LYTRVAINGK SLIGFLDIAV EVNITAKVRL TMDRTGYPRL VIERCDTLLG GIKVKLLRGL LPNLVDNLVN RVLADVLPDL LCPIVDVVLG LVNDQLGLVD SLIPLGILGS VQYTFSSLPL VTGEFLELDL NTLVGEAGGG LIDYPLGWPA VSPKPMPELP PMGDNTKSQL AMSANFLGSV LTLLQKQHAL DLDITNGMFE ELPPLTTATL GALIPKVFQQ YPESCPLIIR IQVLNPPSVM LQKDKALVKV LATAEVMVSQ PKDLETTICL IDVDTEFLAS FSTEGDKLMI DAKLEKTSLN LRTSNVGNFD IGLMEVLVEK IFDLAFMPAM NAVLGSGVPL PKILNIDFSN ADIDVLEDLL VLSA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received.
  • 基因功能参考文献：
    1. LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism. PMID: 28419216
    2. In conclusion, BPIFB4 and CXCR4 expression classify long-lived individuals health status that correlates with maintained mononuclear cell migration. PMID: 28121621
    3. Longevity-associated variant-BPIFB4 may represent a novel therapeutic tool to fight endothelial dysfunction and promote vascular reparative processes. PMID: 26034043
  • 亚细胞定位：
    Secreted. Cytoplasm.
  • 蛋白家族：
    BPI/LBP/Plunc superfamily, BPI/LBP family
  • 组织特异性：
    Expressed in nasal tissue.
  • 数据库链接：

    HGNC: 16179

    OMIM: 615718

    KEGG: hsa:149954

    STRING: 9606.ENSP00000364632

    UniGene: Hs.38961