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  4. Recombinant Human Coiled-coil domain-containing protein 151 (CCDC151)

Recombinant Human Coiled-coil domain-containing protein 151 (CCDC151)

  • 中文名称：
    Recombinant Human Coiled-coil domain-containing protein 151(CCDC151),Yeast
  • 货号：
    CSB-YP004670HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Coiled-coil domain-containing protein 151(CCDC151),Yeast
  • 货号：
    CSB-EP004670HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Coiled-coil domain-containing protein 151(CCDC151),Yeast
  • 货号：
    CSB-EP004670HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Coiled-coil domain-containing protein 151(CCDC151),Yeast
  • 货号：
    CSB-BP004670HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Coiled-coil domain-containing protein 151(CCDC151),Yeast
  • 货号：
    CSB-MP004670HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CCDC151
  • Uniprot No.：
  • 别名：
    CC151_HUMAN; Ccdc151; Coiled coil domain containing 151; Coiled-coil domain-containing protein 151; MGC20983
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-595
  • 氨基酸序列
    MTSPLCRAAS ANALPPQDQA STPSSRVKGR EASGKPSHLR GKGTAQAWTP GRSKGGSFHR GAGKPSVHSQ VAELHKKIQL LEGDRKAFFE SSQWNIKKNQ ETISQLRKET KALELKLLDL LKGDEKVVQA VIREWKWEKP YLKNRTGQAL EHLDHRLREK VKQQNALRHQ VVLRQRRLEE LQLQHSLRLL EMAEAQNRHT EVAKTMRNLE NRLEKAQMKA QEAEHITSVY LQLKAYLMDE SLNLENRLDS MEAEVVRTKH ELEALHVVNQ EALNARDIAK NQLQYLEETL VRERKKRERY ISECKKRAEE KKLENERMER KTHREHLLLQ SDDTIQDSLH AKEEELRQRW SMYQMEVIFG KVKDATGTDE THSLVRRFLA QGDTFAQLET LKSENEQTLV RLKQEKQQLQ RELEDLKYSG EATLVSQQKL QAEAQERLKK EERRHAEAKD QLERALRAMQ VAKDSLEHLA SKLIHITVED GRFAGKELDP QADNYVPNLL GLVEEKLLKL QAQLQGHDVQ EMLCHIANRE FLASLEGRLP EYNTRIALPL ATSKDKFFDE ESEEEDNEVV TRASLKIRSQ KLIESHKKHR RSRRS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule. Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules.
  • 基因功能参考文献：
    1. observed a novel nonsense mutation in a homozygous state in the CCDC151 gene (NM_145045.4:c.925G>T:p.[E309*]) in a clinically diagnosed PCD patient from a consanguineous family of Arabic ancestry PMID: 25224326
    2. CCDC151 mutations cause primary ciliary dyskinesia by disruption of the outer dynein arm docking complex formation. PMID: 25192045
  • 相关疾病：
    Ciliary dyskinesia, primary, 30 (CILD30)
  • 亚细胞定位：
    Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium axoneme.
  • 数据库链接：

    HGNC: 28303

    OMIM: 615956

    KEGG: hsa:115948

    STRING: 9606.ENSP00000348757

    UniGene: Hs.124010