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  4. Recombinant Human Coiled-coil domain-containing protein 28A (CCDC28A)

Recombinant Human Coiled-coil domain-containing protein 28A (CCDC28A)

  • 货号：
    CSB-YP814216HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP814216HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP814216HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP814216HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP814216HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CCDC28A
  • Uniprot No.：
  • 别名：
    CCDC28A; C6orf80; Coiled-coil domain-containing protein 28A; CCRL1AP
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-274
  • 氨基酸序列
    MPRAEPRATL GEQEKAGLPL GAWRLYLLRH FRKQTELRRS GSRDVTGALL VAAAVASEAV GSLRVAEGGP NTLLLQVLRS WPWCNKELKT MEERKVKRRS PKSFSAHCTQ VVNAKKNAIP VSKSTGFSNP ASQSTSQRPK LKRVMKEKTK PQGGEGKGAQ STPIQHSFLT DVSDVQEMER GLLSLLNDFH SGKLQAFGNE CSIEQMEHVR GMQEKLARLN LELYGELEEL PEDKRKTASD SNLDRLLSDL EELNSSIQKL HLADAQDVPN TSAS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. the recurrent NUP98-CCDC28A is an oncogene that induces a rapid and transplantable myeloid neoplasm in recipient mice. They also provide additional evidence for an alternative leukemogenic mechanism for NUP98 oncogenes. PMID: 22058212
  • 相关疾病：
    A chromosomal aberration involving CCDC28A has been identified in acute leukemias. Translocation t(6;11)(q24.1;p15.5) with NUP98. The chimeric transcript is an in-frame fusion of NUP98 exon 13 to CCDC28A exon 2. Ectopic expression of NUP98-CCDC28A in mouse promotes the proliferative capacity and self-renewal potential of hematopoietic progenitors and rapidly induced fatal myeloproliferative neoplasms and defects in the differentiation of the erythro-megakaryocytic lineage.
  • 数据库链接：

    HGNC: 21098

    OMIM: 615353

    KEGG: hsa:25901

    STRING: 9606.ENSP00000332716

    UniGene: Hs.412019