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  4. Recombinant Human Coiled-coil domain-containing protein 34 (CCDC34)

Recombinant Human Coiled-coil domain-containing protein 34 (CCDC34)

  • 中文名称：
    Recombinant Human Coiled-coil domain-containing protein 34(CCDC34),Yeast
  • 货号：
    CSB-YP850308HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Coiled-coil domain-containing protein 34(CCDC34),Yeast
  • 货号：
    CSB-EP850308HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Coiled-coil domain-containing protein 34(CCDC34),Yeast
  • 货号：
    CSB-EP850308HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Coiled-coil domain-containing protein 34(CCDC34),Yeast
  • 货号：
    CSB-BP850308HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Coiled-coil domain-containing protein 34(CCDC34),Yeast
  • 货号：
    CSB-MP850308HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CCDC34
  • Uniprot No.：
  • 别名：
    CCDC34; RAMA3; L15Coiled-coil domain-containing protein 34; Renal carcinoma antigen NY-REN-41
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-373
  • 氨基酸序列
    MWAAGRWGPT FPSSYAGFSA DCRPRSRPSS DSCSVPMTGA RGQGLEVVRS PSPPLPLSCS NSTRSLLSPL GHQSFQFDED DGDGEDEEDV DDEEDVDEDA HDSEAKVASL RGMELQGCAS TQVESENNQE EQKQVRLPES RLTPWEVWFI GKEKEERDRL QLKALEELNQ QLEKRKEMEE REKRKIIAEE KHKEWVQKKN EQKRKEREQK INKEMEEKAA KELEKEYLQE KAKEKYQEWL KKKNAEECER KKKEKEKEKQ QQAEIQEKKE IAEKKFQEWL ENAKHKPRPA AKSYGYANGK LTGFYSGNSY PEPAFYNPIP WKPIHMPPPK EAKDLSGRKS KRPVISQPHK SSSLVIHKAR SNLCLGTLCR IQR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. CCDC34 is overexpressed in esophageal squamous cell carcinoma. PMID: 29397026
    2. Immunohistochemistry showed that expression levels of CCDC34 protein in pancreatic adenocarcinoma were significantly increased, compared with normal pancreas (P=0.000). Patients with pancreatic adenocarcinoma with increased expression of tissue CCDC34 had significantly reduced OS compared with patients with low expression (P=0.000). PMID: 29257799
    3. the present study demonstrated increased expression of CCDC34 protein in CRC tissues was associated with reduced apoptosis and increased metastasis in CRC cell line. PMID: 29115580
    4. CCDC34 is up-regulated in bladder cancer and regulates bladder cancer cell proliferation, apoptosis and migration. PMID: 26312564
  • 相关疾病：
    A chromosomal aberration involving CCDC34 is found in a patient with hamartoma of the retinal pigment epithelium and retina. Translocation t(11;18) (p13;p11.2).
  • 数据库链接：

    HGNC: 25079

    OMIM: 612324

    KEGG: hsa:91057

    STRING: 9606.ENSP00000330240

    UniGene: Hs.143733