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  4. Recombinant Human Craniofacial development protein 1 (CFDP1)

Recombinant Human Craniofacial development protein 1 (CFDP1)

  • 货号：
    CSB-YP005272HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP005272HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP005272HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP005272HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CFDP1
  • Uniprot No.：
  • 别名：
    BCNT; Bucentaur; CENP-29; CFDP1; CFDP1_HUMAN; CP27; Craniofacial development protein 1; p97; Phosphoprotein (Bucentaur); SWC5; Yeti
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-299
  • 氨基酸序列
    MEEFDSEDFS TSEEDEDYVP SGGEYSEDDV NELVKEDEVD GEEQTQKTQG KKRKAQSIPA RKRRQGGLSL EEEEEEDANS ESEGSSSEEE DDAAEQEKGI GSEDARKKKE DELWASFLND VGPKSKVPPS TQVKKGEETE ETSSSKLLVK AEELEKPKET EKVKITKVFD FAGEEVRVTK EVDATSKEAK SFFKQNEKEK PQANVPSALP SLPAGSGLKR SSGMSSLLGK IGAKKQKMST LEKSKLDWES FKEEEGIGEE LAIHNRGKEG YIERKAFLDR VDHRQFEIER DLRLSKMKP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role during embryogenesis.
  • 基因功能参考文献：
    1. Our findings provide new insight into the chromatin functions and mechanisms of the CFDP1 protein and contribute to our understanding of the link between epigenetic regulation and the onset of human complex developmental disorders. PMID: 28367969
    2. Overall, these findings highlight unanticipated evidences suggesting that homodimerization mediated by the BCNT domain is integral to the chromatin functions of BCNT proteins. PMID: 27151176
    3. Bcnt/Cfdp1 is acetylated in vitro by CREB-binding protein (CBP) and four lysine residues including Lys(268) in BCNT-C are also acetylated in vivo, revealing a protein regulated at multiple levels. PMID: 26182435
    4. This study identified rs4888378 in the BCAR1-CFDP1-TMEM170A locus as a novel genetic determinant of carotid intima-media thickness and coronary artery disease risk. PMID: 23152477
    5. includes the region derived from a long interspersed nucleotide PMID: 11831036

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  • 亚细胞定位：
    Chromosome, centromere, kinetochore.
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 1873

    OMIM: 608108

    KEGG: hsa:10428

    STRING: 9606.ENSP00000283882

    UniGene: Hs.461361