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  4. Recombinant Human Cytoplasmic polyadenylation element-binding protein 2 (CPEB2)

Recombinant Human Cytoplasmic polyadenylation element-binding protein 2 (CPEB2)

  • 货号：
    CSB-YP767205HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP767205HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP767205HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP767205HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP767205HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CPEB2
  • Uniprot No.：
  • 别名：
    CPEB2Cytoplasmic polyadenylation element-binding protein 2; CPE-BP2; CPE-binding protein 2; hCPEB-2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-589
  • 氨基酸序列
    MPPPSPDSEN GFYPGLPSSM NPAFFPSFSP VSPHGCTGLS VPTSGGGGGG FGGPFSATAV PPPPPPAMNI PQQQPPPPAA PQQPQSRRSP VSPQLQQQHQ AAAAAFLQQR NSYNHHQPLL KQSPWSNHQS SGWGTGSMSW GAMHGRDHRR TGNMGIPGTM NQISPLKKPF SGNVIAPPKF TRSTPSLTPK SWIEDNVFRT DNNSNTLLPL QVRSSLQLPA WGSDSLQDSW CTAAGTSRID QDRSRMYDSL NMHSLENSLI DIMRAEHDPL KGRLSYPHPG TDNLLMLNGR SSLFPIDDGL LDDGHSDQVG VLNSPTCYSA HQNGERIERF SRKVFVGGLP PDIDEDEITA SFRRFGPLVV DWPHKAESKS YFPPKGYAFL LFQEESSVQA LIDACIEEDG KLYLCVSSPT IKDKPVQIRP WNLSDSDFVM DGSQPLDPRK TIFVGGVPRP LRAVELAMIM DRLYGGVCYA GIDTDPELKY PKGAGRVAFS NQQSYIAAIS ARFVQLQHGD IDKRVEVKPY VLDDQMCDEC QGARCGGKFA PFFCANVTCL QYYCEFCWAN IHSRAGREFH KPLVKEGADR PRQIHFRWN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. Binds to poly(U) RNA oligomers. Required for cell cycle progression, specifically for the transition from metaphase to anaphase.
  • 基因功能参考文献：
    1. Our findings demonstrated the overexpression of miR-885-5p in liver metastasis and its roles in inducing CRC metastasis, potentiating development of miR-885-5p inhibitor to treat advanced CRC in the future. PMID: 28460469
    2. long non-coding RNA CCAT1 regulates the sensitivity of paclitaxel in nasopharyngeal carcinoma cells via miR-181a/CPEB2 axis. PMID: 28358263
    3. findings demonstrate that the regulation of CPEB2 mRNA splicing is a key mechanism in AnR and a driving force in TNBC metastasis PMID: 26304115
    4. Functional studies of the mouse homolog PMID: 12672660
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    RRM CPEB family
  • 数据库链接：

    HGNC: 21745

    OMIM: 610605

    KEGG: hsa:132864

    STRING: 9606.ENSP00000443985

    UniGene: Hs.656937