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  4. Recombinant Human DNL-type zinc finger protein (DNLZ)

Recombinant Human DNL-type zinc finger protein (DNLZ)

  • 货号：
    CSB-YP729194HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP729194HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP729194HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP729194HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP729194HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DNLZ
  • Uniprot No.：
  • 别名：
    BA413M3.2; C9orf151; Chromosome 9 Open Reading Frame 151; DNL type zinc finger; DNL-type zinc finger protein; dnlz; DNLZ_HUMAN; HEP; HEP1; Hsp70-escort protein 1; mtHsp70-escort protein; RP11-413M3.2; TIMM15; Translocase Of Inner Mitochondrial Membrane 15 Homolog (Yeast); Translocase Of Inner Mitochondrial Membrane 15 Homolog; ZIM17
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    50-178
  • 氨基酸序列
    S SEQGPGPAAA LGRVEAAHYQ LVYTCKVCGT RSSKRISKLA YHQGVVIVTC PGCQNHHIIA DNLGWFSDLN GKRNIEEILT ARGEQVHRVA GEGALELVLE AAGAPTSTAA PEAGEDEGPP SPGKTEPS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May function as a co-chaperone towards HSPA9/mortalin which, by itself, is prone to self-aggregation.
  • 基因功能参考文献：
    1. The results indicate that hHep1 shares some structural similarities with the yeast ortholog despite the low identity and functional differences. PMID: 23462535
    2. DNLZ/HEP zinc-binding subdomain is critical for regulation of the mitochondrial chaperone HSPA9. Human DNLZ partially complements the growth of Deltazim17 Saccharomyces cerevisiae. PMID: 22162012
    3. These findings implicate a conserved histidine as critical for DNLZ regulation of mitochondrial HSPA9 catalytic activity. PMID: 21530495
  • 亚细胞定位：
    Mitochondrion.
  • 数据库链接：

    HGNC: 33879

    KEGG: hsa:728489

    STRING: 9606.ENSP00000360803

    UniGene: Hs.528581