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  4. Recombinant Human Deleted in azoospermia protein 4 (DAZ4)

Recombinant Human Deleted in azoospermia protein 4 (DAZ4)

  • 中文名称：
    Recombinant Human Deleted in azoospermia protein 4(DAZ4),Yeast
  • 货号：
    CSB-YP769764HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Deleted in azoospermia protein 4(DAZ4),Yeast
  • 货号：
    CSB-EP769764HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Deleted in azoospermia protein 4(DAZ4),Yeast
  • 货号：
    CSB-EP769764HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Deleted in azoospermia protein 4(DAZ4),Yeast
  • 货号：
    CSB-BP769764HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Deleted in azoospermia protein 4(DAZ4),Yeast
  • 货号：
    CSB-MP769764HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DAZ4
  • Uniprot No.：
  • 别名：
    DAZ4Deleted in azoospermia protein 4
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-579
  • 氨基酸序列
    MSAANPETPN STISREASTQ SSSAAASQGW VLPEGKIVPN TVFVGGIDAR MDETEIGSCF GRYGSVKEVK IITNRTGVSK GYGFVSFVND VDVQKIVGSQ IHFHGKKLKL GPAIRKQKLC ARHVQPRPLV VNPPPPPQFQ NVWRNPNTET YLQPQITPNP VTQHVQSAAN PETPNSTISR EASTQSSSAA ASQGWVLPEG KIVPNTVFVG GIDARMDETE IGSCFGRYGS VKEVKIITNR TGVSKGYGFV SFVNDVDVQK IVGSQIHFHG KKLKLGPAIR KQKLCARHVQ PRPLVVNPPP PPQFQNVWRN PNTETYLQPQ ITPNPVTQHV QAYSAYPHSP GQVITGCQLL VYNYQEYPTY PDSAFQVTTG YQLPVYNYQP FPAYPRSPFQ VTAGYQLPVY NYQAFPAYPN SPFQVATGYQ FPVYNYQPFP AYPSSPFQVT AGYQLPVYNY QAFPAYPNSP FQVATGYQFP VYNYQAFPAY PNSPVQVTTG YQLPVYNYQA FPAYPSSPFQ VTTGYQLPVY NYQAFPAYPN SAVQVTTGYQ FHVYNYQMPP QCPVGEQRRN LWTEAYKWWY LVCLIQRRD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

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靶点详情

  • 功能：
    RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
  • 基因功能参考文献：
    1. Oligospermia seems to be promoted by removing DAZ4 copy. Deletion of DAZ2 and DAZ4 gene copies is associated with male infertility. PMID: 24878370
  • 相关疾病：
    Spermatogenic failure Y-linked 2 (SPGFY2)
  • 亚细胞定位：
    Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
  • 蛋白家族：
    RRM DAZ family
  • 组织特异性：
    Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level).
  • 数据库链接：

    HGNC: 15966

    OMIM: 400003

    KEGG: hsa:57135

    STRING: 9606.ENSP00000401363

    UniGene: Hs.522868