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  4. Recombinant Human Dimethylaniline monooxygenase [N-oxide-forming] 2 (FMO2)

Recombinant Human Dimethylaniline monooxygenase [N-oxide-forming] 2 (FMO2)

  • 中文名称：
    人FMO2重组蛋白
  • 货号：
    CSB-YP857449HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人FMO2重组蛋白
  • 货号：
    CSB-EP857449HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人FMO2重组蛋白
  • 货号：
    CSB-EP857449HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人FMO2重组蛋白
  • 货号：
    CSB-BP857449HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人FMO2重组蛋白
  • 货号：
    CSB-MP857449HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    FMO2
  • Uniprot No.：
  • 别名：
    2310008D08Rik; 2310042I22Rik; AW107733; Dimethylaniline monooxygenase [N oxide forming] 2; Dimethylaniline monooxygenase [N-oxide-forming] 2; Dimethylaniline oxidase 2; Flavin containing monooxygenase 2 (non functional); Flavin containing monooxygenase 2; FLJ40826; FMO 1B1; FMO 2; FMO; FMO pulmonary; FMO1B1; FMO2; FMO2_HUMAN; MGC28212; OTTMUSP00000028686; OTTMUSP00000028687; Pulmonary flavin containing monooxygenase 2; Pulmonary flavin-containing monooxygenase 2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-471
  • 氨基酸序列
    AKKVAVIGA GVSGLISLKC CVDEGLEPTC FERTEDIGGV WRFKENVEDG RASIYQSVVT NTSKEMSCFS DFPMPEDFPN FLHNSKLLEY FRIFAKKFDL LKYIQFQTTV LSVRKCPDFS SSGQWKVVTQ SNGKEQSAVF DAVMVCSGHH ILPHIPLKSF PGMERFKGQY FHSRQYKHPD GFEGKRILVI GMGNSGSDIA VELSKNAAQV FISTRHGTWV MSRISEDGYP WDSVFHTRFR SMLRNVLPRT AVKWMIEQQM NRWFNHENYG LEPQNKYIMK EPVLNDDVPS RLLCGAIKVK STVKELTETS AIFEDGTVEE NIDVIIFATG YSFSFPFLED SLVKVENNMV SLYKYIFPAH LDKSTLACIG LIQPLGSIFP TAELQARWVT RVFKGLCSLP SERTMMMDII KRNEKRIDLF GESQSQTLQT NYVDYLDELA LEIGAKPDFC SLLFKDPKLA VRLYFGPCNS Y
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole.
  • 基因功能参考文献：
    1. study provides an evidence for the existence of an evolutionary adaptation to an ancient disease based on an ancestral genetic variant acting in a FMO2 haplotypic framework in Ethiopian populations PMID: 28981537
    2. analysis of flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics PMID: 15864117
    3. analysis of how the functional variant flavin-containing monooxygenase 2*1 is at high frequency throughout sub-Saharan Africa PMID: 18794725
    4. Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K. PMID: 19420133
  • 亚细胞定位：
    Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族：
    FMO family
  • 组织特异性：
    Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain.
  • 数据库链接：

    HGNC: 3770

    OMIM: 603955

    KEGG: hsa:2327

    STRING: 9606.ENSP00000209929

    UniGene: Hs.144912