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  4. Recombinant Human Epithelial-stromal interaction protein 1 (EPSTI1)

Recombinant Human Epithelial-stromal interaction protein 1 (EPSTI1)

  • 中文名称：
    人EPSTI1重组蛋白
  • 货号：
    CSB-YP839347HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人EPSTI1重组蛋白
  • 货号：
    CSB-EP839347HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人EPSTI1重组蛋白
  • 货号：
    CSB-EP839347HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人EPSTI1重组蛋白
  • 货号：
    CSB-BP839347HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人EPSTI1重组蛋白
  • 货号：
    CSB-MP839347HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    EPSTI1
  • Uniprot No.：
  • 别名：
    BRESI 1; BRESI1; Epithelial stromal interaction 1 (breast); Epithelial stromal interaction protein 1 (breast); Epithelial stromal interaction protein 1; Epithelial-stromal interaction protein 1; EPSTI 1; Epsti1; ESIP1_HUMAN; MGC29634
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-318
  • 氨基酸序列
    MNTRNRVVNS GLGASPASRP TRDPQDPSGR QGELSPVEDQ REGLEAAPKG PSRESVVHAG QRRTSAYTLI APNINRRNEI QRIAEQELAN LEKWKEQNRA KPVHLVPRRL GGSQSETEVR QKQQLQLMQS KYKQKLKREE SVRIKKEAEE AELQKMKAIQ REKSNKLEEK KRLQENLRRE AFREHQQYKT AEFLSKLNTE SPDRSACQSA VCGPQSSTWK LPILPRDHSW ARSWAYRDSL KAEENRKLQK MKDEQHQKSE LLELKRQQQE QERAKIHQTE HRRVNNAFLD RLQGKSQPGG LEQSGGCWNM NSGNSWGI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation. Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages.
  • 基因功能参考文献：
    1. A novel KLF8 to EPSTI1 to VCP to NF-kappaB signaling mechanism potentially critical for breast cancer invasion and metastasis. PMID: 24096480
    2. These observations implicate EPSTI1 as a hitherto unappreciated regulator of tumor cell properties. PMID: 20133812
  • 组织特异性：
    Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vit
  • 数据库链接：

    HGNC: 16465

    OMIM: 607441

    KEGG: hsa:94240

    STRING: 9606.ENSP00000318982

    UniGene: Hs.546467