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  4. Recombinant Human Erythroid membrane-associated protein (ERMAP), partial

Recombinant Human Erythroid membrane-associated protein (ERMAP), partial

  • 中文名称：
    人ERMAP重组蛋白
  • 货号：
    CSB-YP853480HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人ERMAP重组蛋白
  • 货号：
    CSB-EP853480HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人ERMAP重组蛋白
  • 货号：
    CSB-EP853480HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人ERMAP重组蛋白
  • 货号：
    CSB-BP853480HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人ERMAP重组蛋白
  • 货号：
    CSB-MP853480HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ERMAP
  • Uniprot No.：
  • 别名：
    ERMAP; ERMAP_HUMAN; Erythroblast membrane associated protein ; Erythroid membrane associated protein; Erythroid membrane-associated protein; hERMAP; MGC118810; MGC118811; MGC118812; MGC118813; PRO2801; Radin blood group (Rd); Radin blood group antigen; RD; SC; Scianna blood group (Sc); Scianna blood group antigen
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Possible role as a cell-adhesion or receptor molecule of erythroid cells.
  • 基因功能参考文献：
    1. Through molecular genotyping we also identified polymorphisms in RhCE, Kell, Duffy, Colton, Lutheran and Scianna loci in donors and patients. PMID: 25582271
    2. the five known probands with the SC*994C>T silencing nucleotide change were from the Pacific Islands. PMID: 24094239
    3. The human ermap gene plays an important role in differentiation and development of erythroid cells. PMID: 18426659
    4. A human cDNA and gene encoding for human ERMAP is cloned and characterized. The protein is sequenced and its expression analyzed. PMID: 11783959
    5. DNA sequencing demonstrates Scianna antigens including Rd are expressed by ERMAP. PMID: 12393480
    6. ERMAP, a unique member of the B30.2 domain protein family, is expressed in erythroid cells in fetal liver, adult bone marrow, reticulocytes and in circulating erythroblasts in 8-12-week fetal cord blood. PMID: 11549310

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  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Cytoplasm.
  • 蛋白家族：
    Immunoglobulin superfamily, BTN/MOG family
  • 组织特异性：
    Expressed in erythroid-enriched bone marrow (at protein level). Highly expressed in bone marrow and to a lower extent in leukocytes, thymus, lymph node and spleen.
  • 数据库链接：

    HGNC: 15743

    OMIM: 111620

    KEGG: hsa:114625

    STRING: 9606.ENSP00000361592

    UniGene: Hs.439437