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  4. Recombinant Human Forkhead box protein N4 (FOXN4)

Recombinant Human Forkhead box protein N4 (FOXN4)

  • 中文名称：
    人FOXN4重组蛋白
  • 货号：
    CSB-YP850403HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人FOXN4重组蛋白
  • 货号：
    CSB-EP850403HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人FOXN4重组蛋白
  • 货号：
    CSB-EP850403HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人FOXN4重组蛋白
  • 货号：
    CSB-BP850403HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人FOXN4重组蛋白
  • 货号：
    CSB-MP850403HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    FOXN4
  • Uniprot No.：
  • 别名：
    FOXN4Forkhead box protein N4
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-517
  • 氨基酸序列
    MIESDTSSIM SGIIRNSGQN HHPSPQEYRL LATTSDDDLP GDLQSLSWLT AVDVPRLQQM ASGRVDLGGP CVPHPHPGAL AGVADLHVGA TPSPLLHGPA GMAPRGMPGL GPITGHRDSM SQFPVGGQPS SGLQDPPHLY SPATQPQFPL PPGAQQCPPV GLYGPPFGVR PPYPQPHVAV HSSQELHPKH YPKPIYSYSC LIAMALKNSK TGSLPVSEIY SFMKEHFPYF KTAPDGWKNS VRHNLSLNKC FEKVENKMSG SSRKGCLWAL NLARIDKMEE EMHKWKRKDL AAIHRSMANP EELDKLISDR PESCRRPGKP GEPEAPVLTH ATTVAVAHGC LAVSQLPPQP LMTLSLQSVP LHHQVQPQAH LAPDSPAPAQ TPPLHALPDL SPSPLPHPAM GRAPVDFINI STDMNTEVDA LDPSIMDFAL QGNLWEEMKD EGFSLDTLGA FADSPLGCDL GASGLTPASG GSDQSFPDLQ VTGLYTAYST PDSVAASGTS SSSQYLGAQG NKPIALL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development.
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 21399

    OMIM: 609429

    KEGG: hsa:121643

    STRING: 9606.ENSP00000299162

    UniGene: Hs.528316