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  4. Recombinant Human Interferon regulatory factor 2-binding protein-like (IRF2BPL)

Recombinant Human Interferon regulatory factor 2-binding protein-like (IRF2BPL)

  • 中文名称：
    人IRF2BPL重组蛋白
  • 货号：
    CSB-YP887953HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人IRF2BPL重组蛋白
  • 货号：
    CSB-EP887953HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人IRF2BPL重组蛋白
  • 货号：
    CSB-EP887953HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人IRF2BPL重组蛋白
  • 货号：
    CSB-BP887953HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人IRF2BPL重组蛋白
  • 货号：
    CSB-MP887953HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    IRF2BPL
  • Uniprot No.：
  • 别名：
    IRF2BPL; C14orf4; EAP1; KIAA1865; My039; Probable E3 ubiquitin-protein ligase IRF2BPL; EC 2.3.2.27; Enhanced at puberty protein 1; Interferon regulatory factor 2-binding protein-like
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-796
  • 氨基酸序列
    MSAAQVSSSR RQSCYLCDLP RMPWAMIWDF SEPVCRGCVN YEGADRIEFV IETARQLKRA HGCFQDGRSP GPPPPVGVKT VALSAKEAAA AAAAAAAAAA AAQQQQQQQQ QQQQQQQQQQ QQQQQQQLNH VDGSSKPAVL AAPSGLERYG LSAAAAAAAA AAAAVEQRSR FEYPPPPVSL GSSSHTARLP NGLGGPNGFP KPTPEEGPPE LNRQSPNSSS AAASVASRRG THGGLVTGLP NPGGGGGPQL TVPPNLLPQT LLNGPASAAV LPPPPPHALG SRGPPTPAPP GAPGGPACLG GTPGVSATSS SASSSTSSSV AEVGVGAGGK RPGSVSSTDQ ERELKEKQRN AEALAELSES LRNRAEEWAS KPKMVRDTLL TLAGCTPYEV RFKKDHSLLG RVFAFDAVSK PGMDYELKLF IEYPTGSGNV YSSASGVAKQ MYQDCMKDFG RGLSSGFKYL EYEKKHGSGD WRLLGDLLPE AVRFFKEGVP GADMLPQPYL DASCPMLPTA LVSLSRAPSA PPGTGALPPA APSGRGAAAS LRKRKASPEP PDSAEGALKL GEEQQRQQWM ANQSEALKLT MSAGGFAAPG HAAGGPPPPP PPLGPHSNRT TPPESAPQNG PSPMAALMSV ADTLGTAHSP KDGSSVHSTT ASARRNSSSP VSPASVPGQR RLASRNGDLN LQVAPPPPSA HPGMDQVHPQ NIPDSPMANS GPLCCTICHE RLEDTHFVQC PSVPSHKFCF PCSRESIKAQ GATGEVYCPS GEKCPLVGSN VPWAFMQGEI ATILAGDVKV KKERDP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probable E3 ubiquitin protein ligase involved in the proteasome-mediated ubiquitin-dependent degradation of target proteins. Through the degradation of CTNNB1, functions downstream of FOXF2 to negatively regulate the Wnt signaling pathway. Probably plays a role in the development of the central nervous system and in neuronal maintenance (Probable). Also acts as a transcriptional regulator of genes controlling female reproductive function. May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter.
  • 基因功能参考文献：
    1. C14orf4 encodes a transcriptional regulator that, acting within the neuroendocrine brain, contributes to controlling female reproductive function PMID: 17627301
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    IRF2BP family
  • 组织特异性：
    Highly expressed in the heart, moderately in skeletal muscle and pancreas, and weakly in brain, kidney, liver, testis, thyroid gland and lymphocytes.
  • 数据库链接：

    HGNC: 14282

    OMIM: 611720

    KEGG: hsa:64207

    STRING: 9606.ENSP00000238647

    UniGene: Hs.179260