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  4. Recombinant Human Isopentenyl-diphosphate Delta-isomerase 1 (IDI1)

Recombinant Human Isopentenyl-diphosphate Delta-isomerase 1 (IDI1)

  • 中文名称：
    人IDI1重组蛋白
  • 货号：
    CSB-YP619796HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人IDI1重组蛋白
  • 货号：
    CSB-EP619796HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人IDI1重组蛋白
  • 货号：
    CSB-EP619796HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人IDI1重组蛋白
  • 货号：
    CSB-BP619796HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人IDI1重组蛋白
  • 货号：
    CSB-MP619796HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    IDI1
  • Uniprot No.：
  • 别名：
    isopentenyl diphosphate dimethylallyl diphosphate isomerase; IDI1; IDI1_HUMAN; IPP isomerase 1; IPP isomerase; IPPI1; Isopentenyl diphosphate Delta isomerase 1; Isopentenyl diphosphate Delta isomerase; isopentenyl diphosphate dimethylallyl diphosphate isomerase 1 ; Isopentenyl pyrophosphate isomerase 1; Isopentenyl-diphosphate Delta-isomerase 1; OTTHUMP00000018951
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-227
  • 氨基酸序列
    MPEINTNHLD KQQVQLLAEM CILIDENDNK IGAETKKNCH LNENIEKGLL HRAFSVFLFN TENKLLLQQR SDAKITFPGC FTNTCCSHPL SNPAELEESD ALGVRRAAQR RLKAELGIPL EEVPPEEINY LTRIHYKAQS DGIWGEHEID YILLVRKNVT LNPDPNEIKS YCYVSKEELK ELLKKAASGE IKITPWFKII AATFLFKWWD NLNHLNQFVD HEKIYRM
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  • 基因功能参考文献：
    1. The present findings suggest that IDI1 and IDI2 may be associated with the production of cholesterol metabolites in neurons, leading to alpha-synuclein aggregation during the process of Lewy body formation. PMID: 25950736
    2. Within the 40-kb region on 10p15.3 subtelomere, which harbours two genes encoding isopentenyl diphosphate isomerase 1 (IDI1) and IDI2, there was found a segmental copy-number gain in a large proportion of sporadic amyotrophic lateral sclerosis patients. PMID: 20955688
    3. only one of the two isoforms (IDI1) is highly conserved, ubiquitously expressed and most likely responsible for housekeeping isomerase activity PMID: 14629038
  • 亚细胞定位：
    Peroxisome.
  • 蛋白家族：
    IPP isomerase type 1 family
  • 数据库链接：

    HGNC: 5387

    OMIM: 604055

    KEGG: hsa:3422

    STRING: 9606.ENSP00000370748

    UniGene: Hs.283652