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  4. Recombinant Human Lysosomal thioesterase PPT2 (PPT2)

Recombinant Human Lysosomal thioesterase PPT2 (PPT2)

  • 中文名称：
    人PPT2重组蛋白
  • 货号：
    CSB-YP890940HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PPT2重组蛋白
  • 货号：
    CSB-EP890940HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人PPT2重组蛋白
  • 货号：
    CSB-EP890940HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PPT2重组蛋白
  • 货号：
    CSB-BP890940HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人PPT2重组蛋白
  • 货号：
    CSB-MP890940HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PPT2
  • Uniprot No.：
  • 别名：
    PPT2Lysosomal thioesterase PPT2; PPT-2; EC 3.1.2.-; S-thioesterase G14
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    28-302
  • 氨基酸序列
    APA PHRASYKPVI VVHGLFDSSY SFRHLLEYIN ETHPGTVVTV LDLFDGRESL RPLWEQVQGF REAVVPIMAK APQGVHLICY SQGGLVCRAL LSVMDDHNVD SFISLSSPQM GQYGDTDYLK WLFPTSMRSN LYRICYSPWG QEFSICNYWH DPHHDDLYLN ASSFLALING ERDHPNATVW RKNFLRVGHL VLIGGPDDGV ITPWQSSFFG FYDANETVLE MEEQLVYLRD SFGLKTLLAR GAIVRCPMAG ISHTAWHSNR TLYETCIEPW LS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins.
  • 基因功能参考文献：
    1. We identified that PPT2 on chromosome 6p21 is associated with loss of lung function in the Korean population. PMID: 24387323
    2. The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2. PMID: 12855696
  • 亚细胞定位：
    Lysosome.
  • 蛋白家族：
    Palmitoyl-protein thioesterase family
  • 组织特异性：
    Broadly expressed, with highest levels in skeletal muscle.
  • 数据库链接：

    HGNC: 9326

    OMIM: 603298

    KEGG: hsa:9374

    STRING: 9606.ENSP00000354608

    UniGene: Hs.332138