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  4. Recombinant Human Methyltransferase-like protein 21A (METTL21A)

Recombinant Human Methyltransferase-like protein 21A (METTL21A)

  • 中文名称：
    人METTL21A重组蛋白
  • 货号：
    CSB-YP845165HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人METTL21A重组蛋白
  • 货号：
    CSB-EP845165HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人METTL21A重组蛋白
  • 货号：
    CSB-EP845165HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人METTL21A重组蛋白
  • 货号：
    CSB-BP845165HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人METTL21A重组蛋白
  • 货号：
    CSB-MP845165HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    METTL21A
  • Uniprot No.：
  • 别名：
    F119A_HUMAN; FAM119A; Family with sequence similarity 119 member A; HCA557b; Hepatocellular carcinoma-associated antigen 557b; Hypothetical protein LOC151194; LOC151194; Methyltransferase like 21A; Methyltransferase like protein 21A; METTL21A; MGC45373; Protein FAM119A
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-218
  • 氨基酸序列
    MALVPYEETT EFGLQKFHKP LATFSFANHT IQIRQDWRHL GVAAVVWDAA IVLSTYLEMG AVELRGRSAV ELGAGTGLVG IVAALLGAHV TITDRKVALE FLKSNVQANL PPHIQTKTVV KELTWGQNLG SFSPGEFDLI LGADIIYLEE TFTDLLQTLE HLCSNHSVIL LACRIRYERD NNFLAMLERQ FTVRKVHYDP EKDVHIYEAQ KRNQKEDL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8.
  • 基因功能参考文献：
    1. methyltransferase METTL21A is the enzyme responsible for trimethylation of a conserved lysine residue found in several human Hsp70 (HSPA) proteins PMID: 23921388
    2. METTL21A trimethylates Lys-561 in Hsp70 and corresponding residues in other isoforms (Hsc70, BiP) PMID: 23349634
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Methyltransferase superfamily, METTL21 family
  • 数据库链接：

    HGNC: 30476

    OMIM: 615257

    KEGG: hsa:151194

    STRING: 9606.ENSP00000385481

    UniGene: Hs.664764