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  4. Recombinant Human Microfibrillar-associated protein 2 (MFAP2)

Recombinant Human Microfibrillar-associated protein 2 (MFAP2)

  • 中文名称：
    人MFAP2重组蛋白
  • 货号：
    CSB-YP013746HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MFAP2重组蛋白
  • 货号：
    CSB-EP013746HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MFAP2重组蛋白
  • 货号：
    CSB-EP013746HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MFAP2重组蛋白
  • 货号：
    CSB-BP013746HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MFAP2重组蛋白
  • 货号：
    CSB-MP013746HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MFAP2
  • Uniprot No.：
  • 别名：
    MAGP; MAGP-1; MAGP1; MFAP-2; Mfap2; MFAP2_HUMAN; Microfibril associated glycoprotein; Microfibril-associated glycoprotein 1; Microfibrillar associated protein 2; Microfibrillar-associated protein 2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    18-183
  • 氨基酸序列
    QGQ YDLDPLPPFP DHVQYTHYSD QIDNPDYYDY QEVTPRPSEE QFQFQSQQQV QQEVIPAPTP EPGNAELEPT EPGPLDCREE QYPCTRLYSI HRPCKQCLNE VCFYSLRRVY VINKEICVRT VCAHEELLRA DLCRDKFSKC GVMASSGLCQ SVAASCARSC GSC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the elastin-associated microfibrils.
  • 基因功能参考文献：
    1. Our characterization of alternative forms of MAGP2 present in the extracellular space not only enhances diversity of this ECM protein but also provides a previously unrecognized molecular mechanism for regulation of MAGP2 biological activity. PMID: 23201136
    2. Decreased MFAP2 gene expression in the endometrium of patients with implantation failure after in vitro ertilization treatment. PMID: 22885067
    3. These results demonstrate that microfibril-associated glycoprotein-1 is capable of cumulative binding to distinct regions on tropoelastin, with different apparent dissociation constants and different amounts of bound protein. PMID: 15233806
    4. microfibrillar proteins MAGP-1 and MAGP-2 can function outside of their role in elastic fibers to activate a cellular signaling pathway PMID: 16492672
    5. Study suggests a dual role for MAGP1, with extracellular MAGP1A involved in ECM function, and intracellular MAGP1B modulating the expression of genes that function in cell adhesion, migration and control of ECM deposition. PMID: 17692555

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  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    MFAP family
  • 数据库链接：

    HGNC: 7033

    OMIM: 156790

    KEGG: hsa:4237

    STRING: 9606.ENSP00000364685

    UniGene: Hs.389137