Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Human Mucin-19 (MUC19)

Recombinant Human Mucin-19 (MUC19)

  • 货号：
    CSB-YP773598HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP773598HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP773598HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP773598HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP773598HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MUC19
  • Uniprot No.：
  • 别名：
    MUC19; Mucin-19; MUC-19
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    -
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May function in ocular mucus homeostasis.
  • 基因功能参考文献：
    1. results indicate the important role of polymorphic variants of gene MUC19 in the formation of a predisposition to the development of asthma in individuals of Russian ethnicity. PMID: 26845862
    2. data find MUC19 transcripts in salivary glands of seven subjects and demonstrate MUC19 glycoproteins in glandular mucous cells and saliva. PMID: 25512380
    3. Single-nucleotide polymorphism in the MUC19 gene is associated with Crohn's disease . PMID: 23619718
    4. Presence of MUC 19 is suggestive of mucoepidermoid carcinoma PMID: 21072847
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 21072187
    6. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    7. Germline variation of the MUC19 gene is not attributable to the genomewide significant association of the 12q12 locus with Crohn Disease. PMID: 19714762
    8. MUC19 has significant potential to play a role in both physiology and pathophysiology of the middle ear. PMID: 19533339
    9. identification, cloning and expression of mucin 19; expression of this gene is restricted to the mucous cells of various glandular tissues PMID: 12882755
    10. Results suggest that MUC19 is not a major component in human saliva. PMID: 18426393
    11. Reflux laryngitis is associated with down-regulation of mucin gene expression. PMID: 18834073
    12. Observational study of gene-disease association. (HuGE Navigator) PMID: 19068216

    显示更多

    收起更多

  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Expressed corneal epithelial cells, conjunctival goblet and epithelial cells and lacrimal gland cells (at protein level). Expressed by mucous cells of the submandibular gland and submucosal gland of the trachea. Expressed by middle ear epithelial cells.
  • 数据库链接：

    HGNC: 14362

    OMIM: 612170

    KEGG: hsa:283463

    STRING: 9606.ENSP00000395253

    UniGene: Hs.632712