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  4. Recombinant Human Nucleoside diphosphate-linked moiety X motif 6 (NUDT6)

Recombinant Human Nucleoside diphosphate-linked moiety X motif 6 (NUDT6)

  • 中文名称：
    人NUDT6重组蛋白
  • 货号：
    CSB-YP016176HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NUDT6重组蛋白
  • 货号：
    CSB-EP016176HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NUDT6重组蛋白
  • 货号：
    CSB-EP016176HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NUDT6重组蛋白
  • 货号：
    CSB-BP016176HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NUDT6重组蛋白
  • 货号：
    CSB-MP016176HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NUDT6
  • Uniprot No.：
  • 别名：
    NUDT6; FGF2AS; Nucleoside diphosphate-linked moiety X motif 6; Nudix motif 6; EC 3.6.1.-; Antisense basic fibroblast growth factor; Protein GFG
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-316
  • 氨基酸序列
    MRQPLSWGRW RAMLARTYGP GPSAGYRWAS GAQGYVRNPP VGACDLQGEL DRFGGISVRL ARLDALDRLD AAAFQKGLQA AVQQWRSEGR TAVWLHIPIL QSRFIAPAAS LGFCFHHAES DSSTLTLWLR EGPSRLPGYA SHQVGVAGAV FDESTRKILV VQDRNKLKNM WKFPGGLSEP EEDIGDTAVR EVFEETGIKS EFRSVLSIRQ QHTNPGAFGK SDMYIICRLK PYSFTINFCQ EECLRCEWMD LNDLAKTENT TPITSRVARL LLYGYREGFD KIDLTVEELP AVYTGLFYKL YHKELPENYK TMKGID
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May contribute to the regulation of cell proliferation.
  • 基因功能参考文献：
    1. FGF-2 exhibits antitumor activity in vitro and correlates with expression of FGF receptors expression in medulloblastoma cells PMID: 11801566
    2. 18-kDa FGF-2 harbors a C-terminal nonclassical bipartite nuclear localization signal, a portion of which also regulates its nucleolar localization. PMID: 15247275
    3. The aim of this study was to characterize the expression of alternatively spliced FGF-AS transcripts and encoded nudix-motif proteins in normal human tissues and in esophageal adenocarcinoma. PMID: 17569023
    4. hydroxyapatite nanocrystals exposure up-regulated FGF-2 mRNA by 6 fold and increased 18 kDa protein isoform by 40% PMID: 17681892
    5. Thus, survivin, Smac, and PKC alpha might play important roles in the inhibition of apoptosis by FGF-2 in human small cell lung cancer cells. PMID: 18401527

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  • 亚细胞定位：
    Cytoplasm. Nucleus. Mitochondrion. Note=Subcellular location may vary between isoforms.
  • 蛋白家族：
    Nudix hydrolase family
  • 组织特异性：
    Detected in liver, kidney and esophagus (at protein level). Ubiquitous.
  • 数据库链接：

    HGNC: 8053

    OMIM: 606261

    KEGG: hsa:11162

    STRING: 9606.ENSP00000306070

    UniGene: Hs.558459