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  4. Recombinant Human Nucleus accumbens-associated protein 2 (NACC2)

Recombinant Human Nucleus accumbens-associated protein 2 (NACC2)

  • 中文名称：
    人NACC2重组蛋白
  • 货号：
    CSB-YP836187HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NACC2重组蛋白
  • 货号：
    CSB-EP836187HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NACC2重组蛋白
  • 货号：
    CSB-EP836187HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NACC2重组蛋白
  • 货号：
    CSB-BP836187HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NACC2重组蛋白
  • 货号：
    CSB-MP836187HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NACC2
  • Uniprot No.：
  • 别名：
    BTB (POZ) domain containing 14A; BTB domain containing 14A; BTB/POZ domain containing protein 14A; BTB/POZ domain-containing protein 14A; BTBD 14A; BTBD14; NAC-2; NACC2; NACC2_HUMAN; Nucleus accumbens-associated protein 2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-587
  • 氨基酸序列
    MSQMLHIEIP NFGNTVLGCL NEQRLLGLYC DVSIVVKGQA FKAHRAVLAA SSLYFRDLFS GNSKSAFELP GSVPPACFQQ ILSFCYTGRL TMTASEQLVV MYTAGFLQIQ HIVERGTDLM FKVSSPHCDS QTAVIEDAGS EPQSPCNQLQ PAAAAAAPYV VSPSVPIPLL TRVKHEAMEL PPAGPGLAPK RPLETGPRDG VAVAAGAAVA AGTAPLKLPR VSYYGVPSLA TLIPGIQQMP YPQGERTSPG ASSLPTTDSP TSYHNEEDEE DDEAYDTMVE EQYGQMYIKA SGSYAVQEKP EPVPLESRSC VLIRRDLVAL PASLISQIGY RCHPKLYSEG DPGEKLELVA GSGVYITRGQ LMNCHLCAGV KHKVLLRRLL ATFFDRNTLA NSCGTGIRSS TSDPSRKPLD SRVLNAVKLY CQNFAPSFKE SEMNVIAADM CTNARRVRKR WLPKIKSMLP EGVEMYRTVM GSAAASVPLD PEFPPAAAQV FEQRIYAERR GDAATIVALR TDAVNVDLSA AANPAFDAGE EVDGAGSVIQ EVAAPEPLPA DGQSPPQPFE QGGGGPSRPQ TPAAAARRPE GTYAGTL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53.
  • 基因功能参考文献：
    1. RBB is a novel transcriptional repressor and an important regulator of p53 pathway. PMID: 22926524
  • 亚细胞定位：
    Nucleus. Note=Predominantly associated with chromatin.
  • 数据库链接：

    HGNC: 23846

    OMIM: 615786

    KEGG: hsa:138151

    STRING: 9606.ENSP00000277554

    UniGene: Hs.112895