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  4. Recombinant Human Procollagen C-endopeptidase enhancer 2 (PCOLCE2)

Recombinant Human Procollagen C-endopeptidase enhancer 2 (PCOLCE2)

  • 中文名称：
    人PCOLCE2重组蛋白
  • 货号：
    CSB-EP017632HU
  • 规格：
    ￥1344
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP017632HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) PCOLCE2.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP017632HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) PCOLCE2.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    PCOLCE2
  • Uniprot No.：
  • 别名：
    2400001O18Rik; MGC187469; PCOC2_HUMAN; PCOLCE 2; Pcolce2; PCOLE 2; PCOLE2; PCPE 2; PCPE-2; PCPE2; Procollagen C endopeptidase enhancer 2; Procollagen C proteinase enhancer 2; Procollagen C-endopeptidase enhancer 2; Procollagen C-proteinase enhancer 2; Procollagen COOH terminal proteinase enhancer 2; Procollagen COOH-terminal proteinase enhancer 2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 来源：
    E.coli
  • 分子量：
    59.3kDa
  • 表达区域：
    24-415aa
  • 氨基酸序列
    QSPERPVFTCGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGHANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKPTVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQAGKNMSARLTVVCKQCPLLRRGLNYIIMGQVGEDGRGKIMPNSFIMMFKTKNQKLLDALKNKQC
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-SUMO-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
  • 基因功能参考文献：
    1. Procollagen C-endopeptidase protein 2, atherosclerosis and HDL cholesteryl ester catabolism. [Review] PMID: 26218419
    2. Assignment of Pcolce2 gene, which encodes procollagen C-proteinase enhancer protein 2, to human chromosome 3q23. PMID: 12063410
    3. PCPE2 is shown to be a glycoprotein that differs markedly in the nature of its glycosylation from that of PCPE1 PMID: 12393877
    4. Data indicate that PCPE2 accelerates the proteolytic processing of pro-apolipoprotein (apo) AI by enhancing the cleavage of the hexapeptide extension present at the N terminus of apoAI. PMID: 19237735
  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Highly expressed in the heart, trabecular meshwork, pituitary gland, bladder, mammary gland, trachea and placenta and weakly expressed in the brain. Expressed in cartilage.
  • 数据库链接：

    HGNC: 8739

    OMIM: 607064

    KEGG: hsa:26577

    STRING: 9606.ENSP00000295992

    UniGene: Hs.8944