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  4. Recombinant Human Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 (PCMTD1)

Recombinant Human Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 (PCMTD1)

  • 中文名称：
    人PCMTD1重组蛋白
  • 货号：
    CSB-YP850393HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PCMTD1重组蛋白
  • 货号：
    CSB-EP850393HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人PCMTD1重组蛋白
  • 货号：
    CSB-EP850393HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PCMTD1重组蛋白
  • 货号：
    CSB-BP850393HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人PCMTD1重组蛋白
  • 货号：
    CSB-MP850393HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PCMTD1
  • Uniprot No.：
  • 别名：
    PCMD1_HUMAN; PCMTD1; Protein L isoaspartate (D aspartate) O methyltransferase domain containing 1; Protein-L-isoaspartate O-methyltransferase domain-containing protein 1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-357
  • 氨基酸序列
    GGAVSAGED NDDLIDNLKE AQYIRTERVE QAFRAIDRGD YYLEGYRDNA YKDLAWKHGN IHLSAPCIYS EVMEALKLQP GLSFLNLGSG TGYLSTMVGL ILGPFGINHG IELHSDVVEY AKEKLESFIK NSDSFDKFEF CEPAFVVGNC LQIASDSHQY DRIYCGAGVQ KDHENYMKIL LKVGGILVMP IEDQLTQIMR TGQNTWESKN ILAVSFAPLV QPSKNDNGKP DSVGLPPCAV RNLQDLARIY IRRTLRNFIN DEMQAKGIPQ RAPPKRKRKR VKQRINTYVF VGNQLIPQPL DSEEDEKMEE DNKEEEEKDH NEAMKPEEPP QNLLREKIMK LPLPESLKAY LTYFRDK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. No significant association of PLEKHA7 rs11024102, COL11A1 rs3753841 and PCMTD1-ST18 rs1015213 with primary angle closure glaucoma was found among ethnic Han Chinese from Sichuan PMID: 27455018
    2. The three genetic susceptibility loci for primary angle-closure glaucoma did not underlie any major phenotypic diversity in terms of disease severity or progression. PMID: 24474268
    3. In our study, rs1015213 (located in the intergenic region between PCMTD1 and ST18) was associated significantly with primary angle closure. PMID: 23847314
    4. Presence of at least one A allele (AG or AA genotype) for rs1015213 was associated with a shallower anterior chamber depth (-0.07 mm, 95% CI -0.01 to -0.14 mm, p=0.028) after adjusting for age and sex (both p
  • 亚细胞定位：
    Cytoplasm. Membrane; Lipid-anchor.
  • 蛋白家族：
    Methyltransferase superfamily, L-isoaspartyl/D-aspartyl protein methyltransferase family
  • 数据库链接：

    HGNC: 30483

    KEGG: hsa:115294

    STRING: 9606.ENSP00000353739

    UniGene: Hs.671268