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  4. Recombinant Human Pumilio domain-containing protein KIAA0020 (KIAA0020)

Recombinant Human Pumilio domain-containing protein KIAA0020 (KIAA0020)

  • 中文名称：
    人PUM3重组蛋白
  • 货号：
    CSB-YP620879HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PUM3重组蛋白
  • 货号：
    CSB-EP620879HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人PUM3重组蛋白
  • 货号：
    CSB-EP620879HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PUM3重组蛋白
  • 货号：
    CSB-BP620879HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人PUM3重组蛋白
  • 货号：
    CSB-MP620879HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PUM3
  • Uniprot No.：
  • 别名：
    HA-8; HBV X transactivated gene 5 protein; HBV X-transactivated gene 5 protein; HBV XAg-transactivated protein 5; HLA HA8; HLA-HA8; hPUF-A; K0020_HUMAN; Kiaa0020; KIAA0020 protein; MGC8749; Minor histocompatibility antigen HA 8; Minor histocompatibility antigen HA-8; PEN; Penguin homolog; Protein 5 transactivated by hepatitis B virus X antigen (HBxAg); Protein 5 transactivated by hepatitis B virus X antigen; PUF 6; PUF6; Pumilio domain containing protein KIAA0020; Pumilio domain-containing protein KIAA0020; RP11 526D20.2; XTP 5; XTP5
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-648
  • 氨基酸序列
    MEVKGKKQFT GKSTKTAQEK NRFHKNSDSG SSKTFPTRKV AKEGGPKVTS RNFEKSITKL GKKGVKQFKN KQQGDKSPKN KFQPANKFNK KRKFQPDGRS DESAAKKPKW DDFKKKKKEL KQSRQLSDKT NYDIVVRAKQ MWEILRRKDC DKEKRVKLMS DLQKLIQGKI KTIAFAHDST RVIQCYIQYG NEEQRKQAFE ELRDDLVELS KAKYSRNIVK KFLMYGSKPQ IAEIIRSFKG HVRKMLRHAE ASAIVEYAYN DKAILEQRNM LTEELYGNTF QLYKSADHRT LDKVLEVQPE KLELIMDEMK QILTPMAQKE AVIKHSLVHK VFLDFFTYAP PKLRSEMIEA IREAVVYLAH THDGARVAMH CLWHGTPKDR KVIVKTMKTY VEKVANGQYS HLVLLAAFDC IDDTKLVKQI IISEIISSLP SIVNDKYGRK VLLYLLSPRD PAHTVREIIE VLQKGDGNAH SKKDTEVRRR ELLESISPAL LSYLQEHAQE VVLDKSACVL VSDILGSATG DVQPTMNAIA SLAATGLHPG GKDGELHIAE HPAGHLVLKW LIEQDKKMKE NGREGCFAKT LVEHVGMKNL KSWASVNRGA IILSSLLQSC DLEVANKVKA ALKSLIPTLE KTKSTSKGIE ILLEKLST
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells.
  • 基因功能参考文献：
    1. Results indicate that mismatches in minor H antigens HA-8 (KIAA0020) and ACC-1 (BCL2A1) predisposed to chronic graft-versus-host disease (GvHD). PMID: 23480177
  • 亚细胞定位：
    Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome.
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 29676

    OMIM: 609960

    KEGG: hsa:9933

    STRING: 9606.ENSP00000380982

    UniGene: Hs.493309