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  4. Recombinant Human Putative transcription factor Ovo-like 1 (OVOL1)

Recombinant Human Putative transcription factor Ovo-like 1 (OVOL1)

  • 货号：
    CSB-YP017303HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP017303HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP017303HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP017303HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP017303HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    OVOL1
  • Uniprot No.：
  • 别名：
    hOvo1; Ovo homolog like 1; Ovo like 1(Drosophila); Ovo, Drosophila, homolog-like, 1; Ovol1; OVOL1_HUMAN; Putative transcription factor Ovo like 1; Putative transcription factor Ovo-like 1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-267
  • 氨基酸序列
    MPRAFLVKKP CVSTCKRNWS ELPDEERGEI YVPVSLGFCP PQPYREPEPS VAEPPSCPLA LNMSLRDSSY SMAPGPCVVA QLPSEDMGHL TDPQSRDHGF LRTKMKVTLG DSPSGDLFTC RVCQKAFTYQ RMLNRHMKCH NDVKRHLCTY CGKGFNDTFD LKRHVRTHTG VRPYKCSLCD KAFTQRCSLE SHLKKIHGVQ QKYAYKERRA KLYVCEECGC TSESQEGHVL HLKEHHPDSP LLRKTSKKVA VALQNTVTSL LQGSPHL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system.
  • 基因功能参考文献：
    1. OVOL1 is an integral part of the aryl hydrocarbon receptor-mediated mechanism of Filaggrin expression in human keratinocytes. PMID: 28703805
    2. that the OVOL1-OVOL2 axis may actively contribute to cell differentiation and proliferation in the hair bulb PMID: 26873447
    3. OVOL1 is a regulator of trophoblast progenitor cell fate during human trophoblast development. PMID: 26504231
    4. KIF3A and OVOL1 are involved in the development of Atopic dermatitis in the Chinese pediatric population. PMID: 26127003
    5. OVOL1 may play an important role in human skin morphogenesis and tumorigenesis. PMID: 25509883
    6. Association of KIF3A, but not OVOL1 and ACTL9, with atopic eczema in Italian patients PMID: 23278845
    7. Molecular phylogeny of OVOL1, OVOL2 and OVOL3 genes illustrates a conserved C2H2 zinc finger domain coupled by hypervariable unstructured regions in humans and other species PMID: 22737237

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  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expressed in fetal kidney, and also in adult pancreas and placenta. Not expressed in intestine, peripheral blood lymphocytes and ovary.
  • 数据库链接：

    HGNC: 8525

    OMIM: 602313

    KEGG: hsa:5017

    STRING: 9606.ENSP00000337862

    UniGene: Hs.134434