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  4. Recombinant Human Radial spoke head protein 3 homolog (RSPH3)

Recombinant Human Radial spoke head protein 3 homolog (RSPH3)

  • 中文名称：
    人RSPH3重组蛋白
  • 货号：
    CSB-YP769775HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人RSPH3重组蛋白
  • 货号：
    CSB-EP769775HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人RSPH3重组蛋白
  • 货号：
    CSB-EP769775HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人RSPH3重组蛋白
  • 货号：
    CSB-BP769775HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人RSPH3重组蛋白
  • 货号：
    CSB-MP769775HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    RSPH3
  • Uniprot No.：
  • 别名：
    RSPH3; RSHL2; RSP3; Radial spoke head protein 3 homolog; A-kinase anchor protein RSPH3; Radial spoke head-like protein 2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-560
  • 氨基酸序列
    MTVKPAKAAS LARNLAKRRR TYLGGAAGRS QEPEVPCAAV LPGKPGDRNC PEFPPPDRTL GCWATDAAPA AGLCGAGSEP SIAPTSCAGN LPSRPPPLLS PLLASRNPCP WHYLHLSGSH NTLAPTCFKA KLHRKRGSQP PDMASALTDR TSRAPSTYTY TSRPRALPCQ RSRYRDSLTQ PDEEPMHYGN IMYDRRVIRG NTYALQTGPL LGRPDSLELQ RQREARKRAL ARKQAQEQLR PQTPEPVEGR KHVDVQTELY LEEIADRIIE VDMECQTDAF LDRPPTPLFI PAKTGKDVAT QILEGELFDF DLEVKPVLEV LVGKTIEQSL LEVMEEEELA NLRASQREYE ELRNSERAEV QRLEEQERRH REEKERRKKQ QWEIMHKHNE TSQKIAARAF AQRYLADLLP SVFGSLRDSG YFYDPIERDI EIGFLPWLMN EVEKTMEYSM VGRTVLDMLI REVVEKRLCM YEHGEDTHQS PEPEDEPGGP GAMTESLEAS EFLEQSMSQT RELLLDGGYL QRTTYDRRSS QERKFMEERE LLGQDEETAM RKSLGEEELS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia.
  • 基因功能参考文献：
    1. RSPH3 Mutations Cause Primary Ciliary Dyskinesia with Central-Complex Defects and a Near Absence of Radial Spokes. PMID: 26073779
    2. Radial spoke protein 3 is a mammalian protein kinase A-anchoring protein that binds ERK1/2. PMID: 19684019
  • 相关疾病：
    Ciliary dyskinesia, primary, 32 (CILD32)
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium.
  • 蛋白家族：
    Flagellar radial spoke RSP3 family
  • 数据库链接：

    HGNC: 21054

    OMIM: 615876

    KEGG: hsa:83861

    STRING: 9606.ENSP00000252655

    UniGene: Hs.154628