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  4. Recombinant Human Retinitis pigmentosa 9 protein (RP9)

Recombinant Human Retinitis pigmentosa 9 protein (RP9)

  • 中文名称：
    人RP9重组蛋白
  • 货号：
    CSB-YP844700HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人RP9重组蛋白
  • 货号：
    CSB-EP844700HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人RP9重组蛋白
  • 货号：
    CSB-EP844700HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人RP9重组蛋白
  • 货号：
    CSB-BP844700HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人RP9重组蛋白
  • 货号：
    CSB-MP844700HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    RP9
  • Uniprot No.：
  • 别名：
    PAP-1; Pim-1-associated protein; PIM1-associated protein, mouse, homolog of; Retinitis pigmentosa 9 (human); Retinitis pigmentosa 9 protein; Retinitis pigmentosa 9 protein homolog; rp9; RP9_HUMAN; Rp9h
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-221
  • 氨基酸序列
    MSSRPGREDV GAAGARRPRE PPEQELQRRR EQKRRRHDAQ QLQQLKHLES FYEKPPPGLI KEDETKPEDC IPDVPGNEHA REFLAHAPTK GLWMPLGKEV KVMQCWRCKR YGHRTGDKEC PFFIKGNQKL EQFRVAHEDP MYDIIRDNKR HEKDVRIQQL KQLLEDSTSD EDRSSSSSSE GKEKHKKKKK KEKHKKRKKE KKKKKKRKHK SSKSNEGSDS E
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1.
  • 基因功能参考文献：
    1. Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa PMID: 12032732
    2. Has a role in pre-mRNA splicing, further evidence that PAP-1 is indeed the RP9 gene. PMID: 15474994
    3. PAP-1 interacted with Prp3p but not Prp31p in human cells and yeast, and the basic region of PAP-1 and the C-terminal region of Prp3p, regions beside spots found in retinitis pigmentosa mutations, were needed for binding PMID: 15541726
    4. CIR was found to be colocalized with PAP-1 in nuclear speckles. PMID: 15652350
  • 相关疾病：
    Retinitis pigmentosa 9 (RP9)
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Appears to be expressed in a wide range of tissues.
  • 数据库链接：

    HGNC: 10288

    OMIM: 180104

    KEGG: hsa:6100

    STRING: 9606.ENSP00000297157

    UniGene: Hs.326805