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  4. Recombinant Human Rho-related GTP-binding protein RhoN (RND2)

Recombinant Human Rho-related GTP-binding protein RhoN (RND2)

  • 中文名称：
    人RND2重组蛋白
  • 货号：
    CSB-YP019812HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人RND2重组蛋白
  • 货号：
    CSB-EP019812HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人RND2重组蛋白
  • 货号：
    CSB-EP019812HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人RND2重组蛋白
  • 货号：
    CSB-BP019812HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人RND2重组蛋白
  • 货号：
    CSB-MP019812HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    RND2
  • Uniprot No.：
  • 别名：
    ARHN; CTD-3199J23.4; GTP-binding protein Rho7; ras homolog gene family, member N; Rho 7; Rho family GTPase 2; Rho N; Rho related GTP-binding protein RhoN; Rho-related GTP-binding protein Rho7; Rho-related GTP-binding protein RhoN; Rho7; RhoN; Rnd 2; Rnd2; RND2_HUMAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-224
  • 氨基酸序列
    MEGQSGRCKI VVVGDAECGK TALLQVFAKD AYPGSYVPTV FENYTASFEI DKRRIELNMW DTSGSSYYDN VRPLAYPDSD AVLICFDISR PETLDSVLKK WQGETQEFCP NAKVVLVGCK LDMRTDLATL RELSKQRLIP VTHEQGTVLA KQVGAVSYVE CSSRSSERSV RDVFHVATVA SLGRGHRQLR RTDSRRGMQR SAQLSGRPDR GNEGEIHKDR AKSC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily.
  • 基因功能参考文献：
    1. Rho7 expression was increased in the neurons of patients with IE compared with control samples, which indicated that Rho7 may be associated with the progression of IE or act as a potential target for IE treatment. PMID: 29039551
    2. Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers PMID: 11940653
    3. The RND2 mRNA levels increased significantly after gestation in myometria. PMID: 16311049
    4. Rnd2 regulates neurite outgrowth by functioning as the RhoA activator through Pragmin, in contrast to Rnd1 and Rnd3 inhibiting RhoA signaling PMID: 16481321
  • 亚细胞定位：
    Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rho family
  • 组织特异性：
    Highly expressed in testis.
  • 数据库链接：

    HGNC: 18315

    OMIM: 601555

    KEGG: hsa:8153

    STRING: 9606.ENSP00000466680

    UniGene: Hs.603111