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  4. Recombinant Human Ribosomal RNA processing protein 1 homolog A (RRP1)

Recombinant Human Ribosomal RNA processing protein 1 homolog A (RRP1)

  • 中文名称：
    人RRP1重组蛋白
  • 货号：
    CSB-YP020526HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人RRP1重组蛋白
  • 货号：
    CSB-EP020526HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人RRP1重组蛋白
  • 货号：
    CSB-EP020526HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人RRP1重组蛋白
  • 货号：
    CSB-BP020526HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人RRP1重组蛋白
  • 货号：
    CSB-MP020526HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    RRP1
  • Uniprot No.：
  • 别名：
    D21S2056E; NNP 1; NNP-1; NNP1; Nnp1 homolog nucleolar protein; NOP52; Novel nuclear protein 1; Nucleolar protein Nop52; Nucleolar protein, 52-KD; Protein NNP 1; Protein NNP1; Ribosomal RNA processing 1; Ribosomal RNA processing 1 homolog; Ribosomal RNA processing 1 homolog (S. cerevisiae); Ribosomal RNA processing protein 1 homolog A; Ribosomal RNA processing protein 1, S. cerevisiae, homolog of; rrp1; RRP1 like protein; RRP1-like protein; RRP1_HUMAN; RRP1A
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-461
  • 氨基酸序列
    MVSRVQLPPE IQLAQRLAGN EQVTRDRAVR KLRKYIVART QRAAGGFTHD ELLKVWKGLF YCMWMQDKPL LQEELGRTIS QLVHAFQTTE AQHLFLQAFW QTMNREWTGI DRLRLDKFYM LMRMVLNESL KVLKMQGWEE RQIEELLELL MTEILHPSSQ APNGVKSHFI EIFLEELTKV GAEELTADQN LKFIDPFCRI AARTKDSLVL NNITRGIFET IVEQAPLAIE DLLNELDTQD EEVASDSDES SEGGERGDAL SQKRSEKPPA GSICRAEPEA GEEQAGDDRD SGGPVLQFDY EAVANRLFEM ASRQSTPSQN RKRLYKVIRK LQDLAGGIFP EDEIPEKACR RLLEGRRQKK TKKQKRLLRL QQERGKGEKE PPSPGMERKR SRRRGVGADP EARAEAGEQP GTAERALLRD QPRGRGQRGA RQRRRTPRPL TSARAKAANV QEPEKKKKRR E
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a critical role in the generation of 28S rRNA.
  • 基因功能参考文献：
    1. The data suggest that RRP1 is involved not only in competitive binding with fibrillarin to C1QBP on 90S but also in site 2 cleavage in ITS1 of pre-rRNAs at early stages of human ribosome biogenesis. PMID: 25969445
    2. p32 is a new rRNA maturation factor involved in the remodeling from pre-90S particles to pre-40S and pre-60S particles that requires the exchange of FBL for Nop52. PMID: 21536856
    3. NNP-1 expression in neuroblastoma PMID: 12209604
  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    RRP1 family
  • 组织特异性：
    Ubiquitously expressed in fetal and adult tissues.
  • 数据库链接：

    HGNC: 18785

    OMIM: 610653

    KEGG: hsa:8568

    STRING: 9606.ENSP00000417464

    UniGene: Hs.110757