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  4. Recombinant Human Ribosome biogenesis protein NSA2 homolog (NSA2)

Recombinant Human Ribosome biogenesis protein NSA2 homolog (NSA2)

  • 中文名称：
    人NSA2重组蛋白
  • 货号：
    CSB-YP527263HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NSA2重组蛋白
  • 货号：
    CSB-EP527263HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NSA2重组蛋白
  • 货号：
    CSB-EP527263HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NSA2重组蛋白
  • 货号：
    CSB-BP527263HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NSA2重组蛋白
  • 货号：
    CSB-MP527263HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NSA2
  • Uniprot No.：
  • 别名：
    Hairy cell leukemia protein 1; NSA2; NSA2_HUMAN; Ribosome biogenesis protein NSA2 homolog; TGF beta inducible nuclear protein 1 ; TGF-beta-inducible nuclear protein 1; TINP1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-260
  • 氨基酸序列
    MPQNEYIELH RKRYGYRLDY HEKKRKKESR EAHERSKKAK KMIGLKAKLY HKQRHAEKIQ MKKTIKMHEK RNTKQKNDEK TPQGAVPAYL LDREGQSRAK VLSNMIKQKR KEKAGKWEVP LPKVRAQGET EVLKVIRTGK RKKKAWKRMV TKVCFVGDGF TRKPPKYERF IRPMGLRFKK AHVTHPELKA TFCLPILGVK KNPSSPLYTT LGVITKGTVI EVNVSELGLV TQGGKVIWGK YAQVTNNPEN DGCINAVLLV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
  • 基因功能参考文献：
    1. TINP1 promotes cell proliferation and significantly reduces p53 and p21 expression. PMID: 23912275
    2. NSA2, which increases in diabetic nephropathy, may be involved in the actions of TGFbeta1 and contribute to the development of diabetic nephropathy. PMID: 23220173
    3. Data suggest that circulating NSA2 is elevated in diabetic nephropathy patients with albuminuria, and that renal and circulating NSA2 levels are increased in hyperglycemia in experimental models of diabetes. PMID: 22095236
    4. these results demonstrated that NSA2 is a nucleolar protein involved in cell proliferation and cell cycle regulation. PMID: 19932687
    5. The yeast ortholog, Nsa2, is a pre-ribosomal factor that is essential for biogenesis of the large ribosomal subunit. PMID: 16861225

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  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    Eukaryotic ribosomal protein eS8 family, Ribosome biogenesis protein NSA2 subfamily
  • 数据库链接：

    HGNC: 30728

    OMIM: 612497

    KEGG: hsa:10412

    STRING: 9606.ENSP00000296802

    UniGene: Hs.482526