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  4. Recombinant Human SLC2A4 regulator (SLC2A4RG)

Recombinant Human SLC2A4 regulator (SLC2A4RG)

  • 货号：
    CSB-YP021558HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP021558HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP021558HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP021558HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP021558HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC2A4RG
  • Uniprot No.：
  • 别名：
    GEF; GLUT4 enhancer factor; HDBP 1; HDBP-1; HDBP1; Huntington disease gene regulatory region binding protein 1; Huntington disease gene regulatory region-binding protein 1; S2A4R_HUMAN; Si 1 2 19; Si 1 2; SLC2A4 regulator; SLC2A4RG; Zinc finger protein 2 5 Glut4 enhancer factor
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-387
  • 氨基酸序列
    MERPPPRAAG RDPSALRAEA PWLRAEGPGP RAAPVTVPTP PQGSSVGGGF AGLEFARPQE SEPRASDLGA PRTWTGAAAG PRTPSAHIPV PAQRATPGKA RLDEVMAAAA LTSLSTSPLL LGAPVAAFSP EPGLEPWKEA LVRPPGSYSS SSNSGDWGWD LASDQSSPST PSPPLPPEAA HFLFGEPTLR KRKSPAQVMF QCLWKSCGKV LSTASAMQRH IRLVHLGRQA EPEQSDGEED FYYTELDVGV DTLTDGLSSL TPVSPTASMP PAFPRLELPE LLEPPALPSP LRPPAPPLPP PPVLSTVANP QSCHSDRVYQ GCLTPARLEP QPTEVGACPP ALSSRIGVTL RKPRGDAKKC RKVYGMERRD LWCTACRWKK ACQRFLD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'.
  • 基因功能参考文献：
    1. GEF and MEF2A have roles in regulating the GLUT4 promoter PMID: 14630949
    2. Exercise increases MEF2 and GEF DNA binding and imply that these transcription factors could be potential targets for modulating GLUT4 expression in human skeletal muscle. PMID: 16368714
  • 亚细胞定位：
    Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus.
  • 组织特异性：
    According to PubMed:14630949, expressed in heart, skeletal muscle, liver, kidney and pancreas; undetectable in lung, placenta or brain. According to PubMed:14625278, ubiquitously expressed, with lowest expression in brain and ileum.
  • 数据库链接：

    HGNC: 15930

    OMIM: 609493

    KEGG: hsa:56731

    STRING: 9606.ENSP00000266077

    UniGene: Hs.435126