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  4. Recombinant Human Short-chain dehydrogenase/reductase family 9C member 7 (SDR9C7)

Recombinant Human Short-chain dehydrogenase/reductase family 9C member 7 (SDR9C7)

  • 中文名称：
    人SDR9C7重组蛋白
  • 货号：
    CSB-YP854114HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SDR9C7重组蛋白
  • 货号：
    CSB-EP854114HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SDR9C7重组蛋白
  • 货号：
    CSB-EP854114HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SDR9C7重组蛋白
  • 货号：
    CSB-BP854114HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SDR9C7重组蛋白
  • 货号：
    CSB-MP854114HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SDR9C7
  • Uniprot No.：
  • 别名：
    SDR9C7; RDHS; SDROShort-chain dehydrogenase/reductase family 9C member 7; EC 1.1.1.-; Orphan short-chain dehydrogenase/reductase; SDR-O; RDH-S
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-313
  • 氨基酸序列
    MAALTDLSFM YRWFKNCNLV GNLSEKYVFI TGCDSGFGNL LAKQLVDRGM QVLAACFTEE GSQKLQRDTS YRLQTTLLDV TKSESIKAAA QWVRDKVGEQ GLWALVNNAG VGLPSGPNEW LTKDDFVKVI NVNLVGLIEV TLHMLPMVKR ARGRVVNMSS SGGRVAVIGG GYCVSKFGVE AFSDSIRREL YYFGVKVCII EPGNYRTAIL GKENLESRMR KLWERLPQET RDSYGEDYFR IYTDKLKNIM QVAEPRVRDV INSMEHAIVS RSPRIRYNPG LDAKLLYIPL AKLPTPVTDF ILSRYLPRPA DSV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Displays weak conversion of all-trans-retinal to all-trans-retinol in the presence of NADH. Has apparently no steroid dehydrogenase activity.
  • 基因功能参考文献：
    1. Missense mutations in SDR9C7 gene were identified in families with autosomal recessive congenital ichthyosis: two families shared an identical homozygous mutation c.599T > C (p.Ile200Thr) and one family had another homozygous mutation c.214C > T (p.Arg72Trp). The mutations severely affected a stability of the protein. In a patient's skin, SDR9C7 gene expression in the cornified layer was decreased. PMID: 28173123
    2. SDR9C7 promotes esophageal squamous cell carcinoma metastasis partly through regulation of MMP11. PMID: 23341893
  • 相关疾病：
    Ichthyosis, congenital, autosomal recessive 13 (ARCI13)
  • 亚细胞定位：
    Cytoplasm. Note=Granular distribution in the whole cell.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family
  • 组织特异性：
    Expressed in the skin. Expressed in granular and cornified layers of the epidermis (at protein level). Highly expressed in liver.
  • 数据库链接：

    HGNC: 29958

    OMIM: 609769

    KEGG: hsa:121214

    STRING: 9606.ENSP00000293502

    UniGene: Hs.380178