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  4. Recombinant Human Striated muscle preferentially expressed protein kinase (SPEG), partial

Recombinant Human Striated muscle preferentially expressed protein kinase (SPEG), partial

  • 中文名称：
    人SPEG重组蛋白
  • 货号：
    CSB-EP022529HU
  • 规格：
    ￥1344
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    SPEG
  • Uniprot No.：
  • 别名：
    PEG1; Aortic preferentially expressed gene 1; Aortic preferentially expressed protein 1; APEG 1; APEG-1; BPEG; KIAA1297; MGC12676; Nuclear protein marker for differentiated aortic smooth muscle and down regulated with vascular injury; OTTHUMP00000196351; OTTHUMP00000196352; OTTHUMP00000196353; speG; SPEG complex locus; SPEG_HUMAN; SPEGalpha; SPEGbeta; striated muscle preferentially expressed protein kinase; Striated muscle preferentially expressed protein kinase
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 来源：
    E.coli
  • 分子量：
    38.7kDa
  • 表达区域：
    1-113aa
  • 氨基酸序列
    MQKARGTRGEDAGTRAPPSPGVPPKRAKVGAGGGAPVAVAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSCLWLRRCGAQDAGVYSCMAQNE
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal GST-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells.
  • 基因功能参考文献：
    1. SPEG is present in cardiac muscle, where it plays a critical role; therefore, individuals with SPEG mutations additionally present with dilated cardiomyopathy. PMID: 25087613
    2. Genomic rearrangement on APEG1 in arteriosclerosis was studied. PMID: 15784173
    3. the RGD motif might play a role not only in the adhesion of Aortic Preferentially Expressed Protein-1 and extracellular proteins but also in intracellular protein-protein interactions PMID: 16354304
  • 相关疾病：
    Myopathy, centronuclear, 5 (CNM5)
  • 亚细胞定位：
    [Isoform 3]: Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family
  • 组织特异性：
    Isoform 1 is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 is predominantly expressed in the aorta. Isoform 3 appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dediffer
  • 数据库链接：

    HGNC: 16901

    OMIM: 615950

    KEGG: hsa:10290

    STRING: 9606.ENSP00000311684

    UniGene: Hs.21639