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  4. Recombinant Human Synaptic vesicle membrane protein VAT-1 homolog (VAT1)

Recombinant Human Synaptic vesicle membrane protein VAT-1 homolog (VAT1)

  • 中文名称：
    人VAT1重组蛋白
  • 货号：
    CSB-YP857863HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人VAT1重组蛋白
  • 货号：
    CSB-EP857863HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人VAT1重组蛋白
  • 货号：
    CSB-EP857863HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人VAT1重组蛋白
  • 货号：
    CSB-BP857863HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人VAT1重组蛋白
  • 货号：
    CSB-MP857863HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    VAT1
  • Uniprot No.：
  • 别名：
    VAT1; FLJ20230; Membrane protein of cholinergic synaptic vesicles; MGC124668; OTTMUSP00000002784; RP23-328K2.5; Synaptic vesicle membrane protein VAT 1 homolog; Synaptic vesicle membrane protein VAT-1 homolog; VAT 1; VAT1; VAT1_HUMAN; VATI; Vesicle amine transport protein 1; Vesicle amine transport protein 1 homolog (T. californica)
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-393
  • 氨基酸序列
    SDEREVAEA ATGEDASSPP PKTEAASDPQ HPAASEGAAA AAASPPLLRC LVLTGFGGYD KVKLQSRPAA PPAPGPGQLT LRLRACGLNF ADLMARQGLY DRLPPLPVTP GMEGAGVVIA VGEGVSDRKA GDRVMVLNRS GMWQEEVTVP SVQTFLIPEA MTFEEAAALL VNYITAYMVL FDFGNLQPGH SVLVHMAAGG VGMAAVQLCR TVENVTVFGT ASASKHEALK ENGVTHPIDY HTTDYVDEIK KISPKGVDIV MDPLGGSDTA KGYNLLKPMG KVVTYGMANL LTGPKRNLMA LARTWWNQFS VTALQLLQAN RAVCGFHLGY LDGEVELVSG VVARLLALYN QGHIKPHIDS VWPFEKVADA MKQMQEKKNV GKVLLVPGPE KEN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Possesses ATPase activity. Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2).
  • 基因功能参考文献：
    1. We demonstrate that VAT-1 is a novel pathogenic factor in benign prostatic hyperplasia associated with cell proliferation. PMID: 21394740
    2. The role of phospholipase D in the transport of VAT1 to plasma membranes and in phosphatidic acid metabolism in neutrophils is reported. PMID: 20858461
    3. VAT-1 is overexpressed in glioblastomas and functionally involved in glioma cell migration, representing a new component involved in glioma invasion PMID: 19508442
  • 亚细胞定位：
    Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein.
  • 蛋白家族：
    Zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily
  • 组织特异性：
    Expressed in brain. Also expressed in glioblastoma cells.
  • 数据库链接：

    HGNC: 16919

    OMIM: 604631

    KEGG: hsa:10493

    STRING: 9606.ENSP00000347872

    UniGene: Hs.514199