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  4. Recombinant Human Testis-specific serine/threonine-protein kinase 2 (TSSK2)

Recombinant Human Testis-specific serine/threonine-protein kinase 2 (TSSK2)

  • 中文名称：
    人TSSK2重组蛋白
  • 货号：
    CSB-YP850408HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人TSSK2重组蛋白
  • 货号：
    CSB-EP850408HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人TSSK2重组蛋白
  • 货号：
    CSB-EP850408HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人TSSK2重组蛋白
  • 货号：
    CSB-BP850408HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人TSSK2重组蛋白
  • 货号：
    CSB-MP850408HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TSSK2
  • Uniprot No.：
  • 别名：
    DGS-G; DGSG; DiGeorge syndrome protein G; Serine/threonine kinase 22B (spermiogenesis associated); Serine/threonine protein kinase 22B; Serine/threonine-protein kinase 22B; Spermiogenesis associated 2; SPOGA2; STK22B; Testis specific kinase 2; Testis specific serine kinase 2; Testis specific serine threonine kinase 2; Testis specific serine/threonine protein kinase 2; Testis-specific kinase 2; Testis-specific serine/threonine-protein kinase 2; TSK 2; TSK-2; TSK2; TSSK 2; TSSK-2; Tssk2; TSSK2_HUMAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-358
  • 氨基酸序列
    MDDATVLRKK GYIVGINLGK GSYAKVKSAY SERLKFNVAV KIIDRKKTPT DFVERFLPRE MDILATVNHG SIIKTYEIFE TSDGRIYIIM ELGVQGDLLE FIKCQGALHE DVARKMFRQL SSAVKYCHDL DIVHRDLKCE NLLLDKDFNI KLSDFGFSKR CLRDSNGRII LSKTFCGSAA YAAPEVLQSI PYQPKVYDIW SLGVILYIMV CGSMPYDDSD IRKMLRIQKE HRVDFPRSKN LTCECKDLIY RMLQPDVSQR LHIDEILSHS WLQPPKPKAT SSASFKREGE GKYRAECKLD TKTGLRPDHR PDHKLGAKTQ HRLLVVPENE NRMEDRLAET SRAKDHHISG AEVGKAST
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
  • 基因功能参考文献：
    1. n vitro phosphorylation experiments carried out with TSKS (isoform 1) fragments revealed particularly strong phosphorylation of a recombinant N-terminal region representing aa 1-150 of TSKS, indicating that the N-terminus of human TSKS is phosphorylated by human TSSK2. PMID: 26777341
    2. Report evolution of testis-specific kinases TSSK1B and TSSK2 in primates. PMID: 23258646
    3. associated with male idiopathic infertility PMID: 19926886
    4. Data show that human testis-specific serine/threonine (Ser/Thr) kinase (TSSK) 1 and 2 messages are expressed exclusively in the testis and suggest that this family of kinases might play a role in sperm function. PMID: 15044604
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family
  • 组织特异性：
    Testis-specific. Present in mature spermatozoa (at protein level).
  • 数据库链接：

    HGNC: 11401

    OMIM: 610710

    KEGG: hsa:23617

    STRING: 9606.ENSP00000382544

    UniGene: Hs.694070