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Recombinant Human Thioredoxin-like protein 4B (TXNL4B)

  • 中文名称:
    人TXNL4B重组蛋白
  • 货号:
    CSB-EP868342HU
  • 规格:
    ¥1344
  • 图片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

产品详情

  • 纯度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    TXNL4B
  • Uniprot No.:
  • 别名:
    AI595343; D530025J19Rik; Dim1 like protein; Dim1-like protein; DIM2; DLP; FLJ20511; MGC109322; RGD1305127; Thioredoxin like 4B; Thioredoxin like protein 4B; Thioredoxin-like protein 4B; TXN4B_HUMAN; Txnl4b
  • 种属:
    Homo sapiens (Human)
  • 蛋白长度:
    Full Length
  • 来源:
    E.coli
  • 分子量:
    44.0kDa
  • 表达区域:
    1-149aa
  • 氨基酸序列
    MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLVDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNIPKYDLLYQDI
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签:
    N-terminal GST-tagged
  • 产品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液:
    Tris-based buffer,50% glycerol
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition.
  • 基因功能参考文献:
    1. A crystal structure of TXNL4B was determined at 1.33 A resolution and refined to an Rwork of 0.13 and an Rfree of 0.18 with one native dimer in the asymmetric unit. PMID: 23519793
    2. DLP is implicated in not only cell cycle progression but also in a more specific molecular process such as pre-mRNA splicing PMID: 15161931
    3. crystal structure; in contrast to hDim1, hDim2 forms stable homodimers PMID: 16142897
    4. The human gene coding for the spliceosomal protein thioredoxin-like 4B (TXNL4B) was overexpressed in Escherichia coli and the encoded protein was purified and crystallized. PMID: 16511018
  • 亚细胞定位:
    Nucleus.
  • 蛋白家族:
    DIM1 family
  • 数据库链接:

    HGNC: 26041

    OMIM: 617722

    KEGG: hsa:54957

    STRING: 9606.ENSP00000268483

    UniGene: Hs.134406