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  4. Recombinant Human Transcription factor ETV7 (ETV7)

Recombinant Human Transcription factor ETV7 (ETV7)

  • 中文名称：
    人ETV7重组蛋白
  • 货号：
    CSB-YP897576HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人ETV7重组蛋白
  • 货号：
    CSB-EP897576HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人ETV7重组蛋白
  • 货号：
    CSB-EP897576HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人ETV7重组蛋白
  • 货号：
    CSB-BP897576HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人ETV7重组蛋白
  • 货号：
    CSB-MP897576HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ETV7
  • Uniprot No.：
  • 别名：
    ETS related protein Tel2; Ets transcription factor TEL-2b; Ets transcription factor TEL2; ETS translocation variant 7; ets variant 7; ets variant gene 7 (TEL2 oncogene); ets variant gene 7; ETS-related protein Tel2; ETV7; ETV7_HUMAN; TEL 2; Tel related Ets factor ; Tel-related Ets factor; TEL2 ; TEL2 oncogene; TELB; Transcription factor ETV7; Transcription factor Tel 2; Transcription factor Tel-2; TREF
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-341
  • 氨基酸序列
    MQEGELAISP ISPVAAMPPL GTHVQARCEA QINLLGEGGI CKLPGRLRIQ PALWSREDVL HWLRWAEQEY SLPCTAEHGF EMNGRALCIL TKDDFRHRAP SSGDVLYELL QYIKTQRRAL VCGPFFGGIF RLKTPTQHSP VPPEEVTGPS QMDTRRGHLL QPPDPGLTSN FGHLDDPGLA RWTPGKEESL NLCHCAELGC RTQGVCSFPA MPQAPIDGRI ADCRLLWDYV YQLLLDTRYE PYIKWEDKDA KIFRVVDPNG LARLWGNHKN RVNMTYEKMS RALRHYYKLN IIKKEPGQKL LFRFLKTPGK MVQDKHSHLE PLESQEQDRI EFKDKRPEIS P
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity.
  • 基因功能参考文献：
    1. LTF (lactotransferrin/lactoferrin), and ETV7 (Ets variant 7) were mainly related with cell apoptosis and immune responses. PMID: 29279524
    2. TEL2 plays a key role in nasopharyngeal carcinoma metastasis by directly down-regulating SERPINE1. PMID: 26335051
    3. Human TEL2 augments the proliferation and survival of normal mouse B cells and dramatically accelerates lymphoma development in Emu-Myc transgenic mice. PMID: 15743832
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    ETS family
  • 组织特异性：
    Expressed in hematopoietic tissues.
  • 数据库链接：

    HGNC: 18160

    OMIM: 605255

    KEGG: hsa:51513

    STRING: 9606.ENSP00000341843

    UniGene: Hs.272398