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  4. Recombinant Human Transcription factor SOX-21 (SOX21)

Recombinant Human Transcription factor SOX-21 (SOX21)

  • 中文名称：
    人SOX21重组蛋白
  • 货号：
    CSB-YP896749HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SOX21重组蛋白
  • 货号：
    CSB-EP896749HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SOX21重组蛋白
  • 货号：
    CSB-EP896749HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SOX21重组蛋白
  • 货号：
    CSB-BP896749HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SOX21重组蛋白
  • 货号：
    CSB-MP896749HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    SOX A; SOX-A; sox21; SOX21_HUMAN; SOX25; SRY (sex determining region Y) box 21; SRY; SRY box 21; Transcription factor SOX 21; Transcription factor Sox-21
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-276
  • 氨基酸序列
    MSKPVDHVKR PMNAFMVWSR AQRRKMAQEN PKMHNSEISK RLGAEWKLLT ESEKRPFIDE AKRLRAMHMK EHPDYKYRPR RKPKTLLKKD KFAFPVPYGL GGVADAEHPA LKAGAGLHAG AGGGLVPESL LANPEKAAAA AAAAAARVFF PQSAAAAAAA AAAAAAGSPY SLLDLGSKMA EISSSSSGLP YASSLGYPTA GAGAFHGAAA AAAAAAAAAG GHTHSHPSPG NPGYMIPCNC SAWPSPGLQP PLAYILLPGM GKPQLDPYPA AYAAAL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role as an activator of transcription of OPRM1.
  • 基因功能参考文献：
    1. SOX21-AS1 could be a potential prognostic biomarker . PMID: 29772433
    2. The tumorigenic effect of lncRNA SOX21-AS1 in CRC cells via targeting miR-145/MYO6, providing a novel insight for CRC carcinogenesis. PMID: 29217166
    3. Tumors originating from glioma cells with an induced expression of Sox21 exhibited an increased formation of Sox2:Sox21 complexes and an upregulation of S100beta, CNPase and Tuj1 PMID: 23463365
    4. suggest that Sox21 can negatively regulate Sox2 in glioma. Our findings imply that Sox2 and Sox21 may be interesting targets for the development of novel glioma therapy PMID: 20824710
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 11197

    OMIM: 604974

    KEGG: hsa:11166

    STRING: 9606.ENSP00000366144

    UniGene: Hs.187577